Browsing by Author "Arpa, Muhammet Davut"
Now showing items 1-8 of 8
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Azelaic acid loaded chitosan and HPMC based hydrogels for treatment of acne: Formulation, characterization, in vitro-ex vivo evaluation
Arpa, Muhammet Davut; Seçen, İkbal Merve; Erim, Ümit Can; Hoş, Ayşegül; Üstündağ Okur, Neslihan (Taylor & Francis Ltd, 2022)In this study, hydrogels containing azelaic acid were developed using chitosan or HPMC (1-7%) for local treatment of acne vulgaris. Physicochemical properties such as viscosity, pH and mechanical properties were evaluated. ... -
Chitosan-based buccal mucoadhesive patches to enhance the systemic bioavailability of tizanidine
Arpa, Muhammet Davut; Üstündağ Okur, Neslihan; Gök, Mehmet Koray; Özgümüş, Saadet; Cevher, Erdal (Elsevier B.V., 2023)Tizanidine hydrochloride (TZN) is a muscle relaxant used to treat a variety of disorders such as painful muscle spasms and chronic spasticity. TZN has low oral bioavailability due to extensive first-pass metabolism and is ... -
Design of IKVAV peptide/gold nanoparticle decorated, micro/nano-channeled PCL/PLGA film scaffolds for neuronal differentiation and neurite outgrowth
Aydeğer, Asel; Ayşit, Neşe; Baydaş, Gülsena; Çakıcı, Çağrı; Erim, Ümit Can; Arpa, Muhammet Davut; Özçiçek, İlyas (Elsevier Ltd, 2023)In the field of neural tissue engineering, intensive efforts are being made to develop tissue scaffolds that can support an effective functional recovery and neural development by guiding damaged axons and neurites. ... -
Development and evaluation of mesoporous montmorillonite/magnetite nanocomposites loaded with 5-Fluorouracil
Çiftçi, Hakan; Arpa, Muhammet Davut; Gülaçar, İsmail Musab; Özcan, Levent; Ersoy, Bahri (Elsevier, 2020)Porous magnetic nanomaterials have attracted great attention in a variety of applications, particularly in the magnetically targeted and/or controlled release of various species. In this study, a new route was determined ... -
Formulation, characterization and in vitro release studies of terbinafine hydrochloride loaded buccal films
Arpa, Muhammet Davut; Ünükür, Melike Zeynep; Erim, Ümit Can (Marmara University, 2021)Buccal administration of different active ingredients as an alternative to oral or dermal routes has been widely studied. The films are one of the most investigated dosage forms regarding the buccal formulations developed ... -
New therapeutic system based on hydrogels for vaginal candidiasis management: Formulation-characterization andin vitroevaluation based on vaginal irritation and direct contact test
Arpa, Muhammet Davut; Yoltaş, Ayşegül; Onay Tarlan, Ecehan; Şahin Şenyüz, Cemre; Sipahi, Hande; Aydın, Ahmet; Üstündağ Okur, Neslihan (Taylor and Francis Ltd., 2020)The objective of the present research was to examine the possible usage of terbinafine loaded hydrogels for vaginal application as part of vaginal candidiasis treatment. Vaginal candidiasis belongs to the most frequent ... -
Novel benzydamine hydrochloride and chlorhexidine gluconate loaded bioadhesive films for local treatment of buccal infections
Arpa, Muhammet Davut; Yağcılar, Ayşe Pınar; Biltekin, Sevde Nur (Editions de Sante, 2023)Benzydamine hydrochloride (BZD), chlorhexidine gluconate (CHG) or their combination are frequently used as liquid dosage forms for the local treatment of buccal fungal and bacterial infections. However, the short residence ... -
Preparation and evaluation of novel microemulsion-based hydrogels for dermal delivery of benzocaine
Üstündağ Okur, Neslihan; Çağlar, Emre Şefik; Arpa, Muhammet Davut; Karasulu, Hatice Yeşim (Taylor & Francis Ltd, 2017)The purpose of the current research was to prepare and evaluate the potential use of microemulsion-based hydrogel (MBH) formulations for dermal delivery of benzocaine (BZN). The pseudoternary-phase diagrams were constructed ...
