Browsing by Author "İstanbullu Tosun, Ayşe"
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Anticandidal activities of lactic acid bacteria isolated from the vagina
Er, Sevda; İstanbullu Tosun, Ayşe; Arık, Gizem; Kıvanç, Merih (Tübitak Scientific & Technical Research Council Turkey, 2019)Background/aim: Lactic acid bacteria prevent the overgrowth of pathogenic agents and opportunistic pathogens in the vagina. Moreover, lactic acid bacteria contribute to the preservation of vaginal microbiota by producing ... -
Can hematological parameters be used for differential diagnosis in rotavirus infection at any age of children? A 6-year outcomes from a tertiary referral center
Aksoy Okan, Meliha; Temel, Hayrettin; Okur, Mesut; İstanbullu Tosun, Ayşe (Galenos Publishing House, 2021)Aim: Routine blood parameters are widely used to detect of infectious diseases. Our study aimed to investigate the hematological parameters changes in rotavirus (RV) acute gastroenteritis and to evaluate the value of these ... -
Candida auris Fungemia and a local spread taken under control with infection control measures: First report from Turkey
Kurt, Ahmet Furkan; Kuşkucu, Mert; Balkan, İlker İnanç; Bayri Barış, Ayşe; Yazgan, Zeynep; Öz, Ayşe Şerife; İstanbullu Tosun, Ayşe; Mete, Bilgül; Tabak, Fehmi; Aygün, Gökhan (NLM (Medline), 2021)Candidaauris, draws attention as a new emerging antifungal resistant pathogen, leading to healthcare-associated infections and outbreaks. This is the first report of C. auris fungemia in a 81-year-old patient, confirmed ... -
Carbapenem resistance; surveillance data of 2013-2017
Güven, Özlem; İstanbullu Tosun, Ayşe; Sever, Canan (Bulgarian Society for Microbiology (Union of Scientists in Bulgaria), 2018)The aim of the study was to investigate the status of intestinal colonization with CRE in patients admitted to Istanbul Medipol University Hospital. CRE prevalence was found in 4.1% of specimens collected between January ... -
Clinical and laboratory comparison of Covid-19 and influenza A/B in children
Temel, Hayrettin; Okur, Mesut; Gündüz, Mehmet; Cömert, Murat; Erkesim, Remzi; Çelebi, Merve; İstanbullu Tosun, Ayşe; Ülfer, Gözde (Verlag Klinisches Labor GmbH, 2021)Background: The clinical picture of COVID-19 shows significant similarity with influenza. In this study, it was aimed to compare the clinical and laboratory findings between pediatric patients diagnosed with COVID-19 and ... -
A comparison of the clinical and laboratory characteristics of influenza A and B infections in children
Temel, Hayrettin; Gündüz, Mehmet; Köprülü, Gökçe Nur; Karaman, Sümeyye; Cebeci, Merve; Doğan, Mehmet Sait; İstanbullu Tosun, Ayşe; Okur, Mesut (Life Health and Social Services Foundation, 2021)Aim: In this study, we aimed to compare the clinical and laboratory findings of Influenza A and Influenza B infections in children. Methods: The study included 1826 pediatric patients (aged <16 years) who were di¬agnosed ... -
Demir eksikliği anemisi olan ve olmayan bireylerde serum sialik asit düzeyleri
Ülfer, Gözde; İstanbullu Tosun, Ayşe; Olmuşçelik, Oktay; Yiğitbaşı, Türkan; Çakıcı, Çağrı; Bayramoğlu, Feyza; Emekli, Nesrin (2017)Amaç: Bu çalışmanın amacı demir eksikliği anemisi (DEA) parametreleri ile serum total sialik asit (SA) değerleri arasındaki ilişkinin incelenmesidir. Yöntemler: Çalışmada DEA olan 30 hasta ve 30 sağlıklı kişide serum total ... -
Detection of O25b-ST131 clone, CTX-M-1 and CTX-M-15 genes via real-time PCR in Escherichia coli strains in patients with UTIs obtained from a university hospital in Istanbul
Demirci, Mehmet; Ünlü, Özge; İstanbullu Tosun, Ayşe (Elsevier Ltd, 2019)Background: Escherichia coli sequence type 131 is an important multidrug resistant clone responsible from more than half of ESBL-producing E.coli isolates. Aim of this study was to investigate the presence of O25b-ST131 ... -
Development of a new multiplex real-time PCR assay for rapid screening of hospital-acquired infection agents
İstanbullu Tosun, Ayşe; Kolukırık, Mustafa; Yılmaz, Mesut; Nar Ötgün, Selin; Aygün, Gökhan; Ketre Kolukırık, Canan Zöhre; Zeybek, Ümit; Girgin Özgümüş, Gözde; Turan, Meral; Kuşkucu, Mert; İnce, Orhan; İnce, Bahar; Kılıç, Selçuk (Elsevier B.V., 2023)Aims: A new multiplex real-time PCR (qPCR) assay was developed to detect antibiotic-resistant hospital-acquired infectious agents in nasal and rectal swab samples in 1.5 h without the need for nucleic acid extraction. ... -
Epidemic Klebsiella pneumoniae ST258 incidence in ICU patients admitted to a university hospital in Istanbul
Ünlü, Özge; Ersöz, Berken Rabun; İstanbullu Tosun, Ayşe; Demirci, Mehmet (Journal of Infection in Developing Countries, 2021)Introduction: Klebsiella pneumoniae sequence type 258 (ST258) strains are globally distributed multi-drug resistant pathogens and can spread rapidly throughout the world, causing severe healthcare-associated invasive ... -
Epidemiology of nosocomial candidemia, mortality, and antifungal resistance: 7-year experience in Turkey
Aydın, Selda; Derin, Okan; Şahin, Meyha; Dinleyici, Rümeysa; Yılmaz, Mesut; Ceylan, Bahadır; İstanbullu Tosun, Ayşe; Öztürk, Recep; Mert, Ali (National Institute of Health, 2022)Candidemia is an important clinical condition that prolongs hospital stays and increases morbidity, mortality, and hospital costs. The aim of this retrospective study was to evaluate the epidemiological and microbiological ... -
Evaluation of the clinical features of 81 patients with covid-19: An unpredictable disease in children
Temel, Hayrettin; Gündüz, Mehmet; Arslan, Hüseyin; Ünal, Füsun; Atağ, Emine; Cömert, Murat; Doğan, Mehmet Sait; Erkesim, Remzi; Okur, Mesut; Öktem, Sedat; İstanbullu Tosun, Ayşe (Georg Thieme Verlag, 2021)Objective Data on the prognosis of clinical features of pediatric patients affected by the coronavirus disease 2019 (COVID-19) pandemic is insufficient. This study aimed to examine the clinical, laboratory, and radiology ... -
Evaluation of the synergy of ceftazidime/avibactam in combination with colistin, doripenem, levofloxacin, tigecycline, and tobramycin against OXA-48 producing enterobacterales
Mataracı Kara, Emel; Yılmaz, Mesut; İstanbullu Tosun, Ayşe; Özbek Çelik, Berna (Taylor and Francis Ltd., 2020)This study aims to analyze the effect of ceftazidime/avibactam plus various antibiotics against OXA-48-producing Enterobacterales isolated from Intensive Care Units. Seventy-four non-duplicate OXA-48-producing Enterobacterales ... -
The importance of neutrophil/lymphocyte and lymphocyte/monocyte ratios in the diagnosis of influenza in children
Temel, Hayrettin; Gündüz, Mehmet; İstanbullu Tosun, Ayşe; Çelebi, Merve; Okur, Mesut (Verlag Klinisches Labor GmbH, 2021)Background: We aimed to analyze the neutrophil/lymphocyte ratio (NLR) and lymphocyte/monocyte ratio (LMR) to investigate their value in supporting the diagnosis of influenza in cases with influenza-like symptoms. Methods: ... -
İdrar yolu infeksiyonlarından izole edilen Escherichia Coli ve Klebsiella Pneumoniae suşlarının antimikrobiyal direnç oranları
İstanbullu Tosun, Ayşe; Demirci, Mehmet; Yılmaz, Mesut; Şen, Hatice; Sirekbasan, Leyla; Gözün Şaylan, Ezgi; Gökçeağaçlı, Cemile; Şengil, Ahmet Zeki (2016)İdrar yolu infeksiyonları (İYİ) ülkemizde ve dünyada yatan ve ayaktan hastalarda en sık rastlanan infeksiyonların başında gelmekte ve önemli bir morbidite nedeni olarak karşımıza çıkmaktadır. İdrar yolu infeksiyonlarına ... -
Lower respiratory system infections bacterial agents of adults and children in istanbul, a case study by Medipol Mega Hospital
Ahmed, Mohammed Mohammed (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2017)The general objectives of the study were to explore the incidence of lower respiratory infections due to bacterial pneumonias and to determine antimicrobial susceptibility patterns of infectious agents. The study participants ... -
Özel bir üniversitedeki öğrencilerin cinsel yolla bulaşan enfeksiyonlar hakkındaki bilgi düzeylerinin incelenmesi
Çetin, Canan (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2015)Amaç: Araştırma, İstanbul Medipol Üniversitesi Sağlık Bilimleri Fakültesi 4. sınıf öğrencilerinin cinsel yolla bulaşan enfeksiyonlar hakkındaki bilgi düzeylerinin incelenmesi amacıyla tanımlayıcı olarak yapıldı. Materyal ... -
Relationship between serum osteopontin level and atrial fibrillation recurrence in patients undergoing cryoballoon catheter ablation
Güneş, Hacı Murat; Babur Güler, Gamze; Güler, Ekrem; Demir, Gültekin Günhan; Kızılırmak Yılmaz, Filiz; Omaygenç, Mehmet Onur; İstanbullu Tosun, Ayşe; Akgün, Taylan; Boztosun, Bilal; Kılıçaslan, Fethi (Turkish Society of Cardiology, 2017)Objective: Atrial fibrillation (AF) is the most common sustained arrhythmia and is associated with increased morbidity and mortality. Atrial fibrosis augments recurrence rate following AF catheter ablation. Osteopontin is ... -
Severe acute respiratory syndrome coronavirus-2 antigens and antibodies in breast milk
Keskindemirci, Gonca; Karabayır, Nalan; İstanbullu Tosun, Ayşe; Hançerli Torun, Selda; Altay, Ceren Sultan; Sebirli, Muhammet; Kaba, Özge; Kibar, Büşra Sultan; Gökçay, Gülbin (Istanbul University, 2021)Objective: This study aimed to determine the presence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) antigens and IgM and IgG antibodies in breast milk of mothers diagnosed with Coronavirus disease-19 ... -
Should be remembered in the differential diagnosis of klatskin Tumour: Alveolar echinococcosis
Saka, Burcu; Ünlü Akhan, Aslı; Erol, Cengiz; İstanbullu Tosun, Ayşe; Ertuǧrul, Gökhan (NLM (Medline), 2020)Alveolar echinococcosis is an infectious disease caused by Echinococcus multilocularis and it is frequently diagnosed as a space-occupying lesion in the liver. The growth pattern may be similar to that of a malignant tumour ...