Browsing by Author "Çelik, Eşref"
Now showing items 1-9 of 9
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Chemogenetic inhibition of MCH neurons does not alter memory performance in mice
Mutlu Burnaz, Özlem; Yuluğ, Burak; Öncül, Merve; Çelik, Eşref; Sayar Atasoy, Nilüfer; Çankaya, Şeyda; Hanoğlu, Lütfü; Velioğlu, Halil Aziz (Elsevier Masson s.r.l., 2022)Memory storage in the brain is one of the most extensively studied subjects in neuroscience. However, due to the highly complex structure of the memory-related systems in the brain, the mystery remains unsolved. Consolidation ... -
Impaired melanocortin pathway function in prader-willi syndrome gene-magel2 deficient mice
Öncül, Merve; Dilsiz, Pelin; Ateş Öz, Edanur; Ateş, Tayfun; Aklan, İltan; Çelik, Eşref; Sayar Atasoy, Nilüfer; Atasoy, Deniz (Oxford University Press, 2018)Prader-Willi Syndrome (PWS) is a neurodevelopmental disorder causing social and learning deficits, impaired satiety and severe childhood obesity. Genetic underpinning of PWS involves deletion of a chromosomal region with ... -
Miyelin interaktomu: İkili graf tabanlı protein-protein etkileşimli ağlarla multipl skleroz'da hücre-hücre etkileşimlerinin tanımlanması
Çelik, Eşref (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2018)Miyelin kılıfı, bilginin nöronlar üzerinde verimli transferini sağlar ve nöronların işlevi ve sağ kalımı için elzemdir. Miyelin gelişiminde gözlenen bozuklukların veya miyelin hasarının (demiyelinizasyon), elektriksel ... -
Multiple sclerosis biomarker candidates revealed by cell-type-specific interactome analysis
Yurduseven, Kübra; Babal, Yigit Koray; Çelik, Eşref; Kerman, Bilal Ersen; Aksan Kurnaz, Işıl (Mary Ann Liebert, 2022)Multiple sclerosis (MS) is a demyelinating disorder that affects multiple regions of the central nervous system such as the brain, spinal cord, and optic nerves. Susceptibility to MS, as well as disease progression rates, ... -
Myelin disorders and stem cells: As therapies and models
Aydınlı, Fatmagül İlayda; Çelik, Eşref; Kurt Vatandaşlar, Burcu; Kerman, Bilal Ersen (Tubitak Scientific & Technical Research Council, 2016)Myelin disorders burden millions of people around the world, yet existing therapies are inadequate to cure them. Current remedies commonly treat the symptoms with minimal to no effect on the actual cause of the disorder. ...
