Browsing by Author "Çağlar, Emre Şefik"
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Comparison of 3 doses of aloe vera and burn drugs in market on burnt rat models
Macit, Çağlar; Tatlıpınar, Mücteba Eşref; Çağlar, Emre Şefik; Taner, Neda; Turgut, Senanur; Sarıkaya, Elif Görkem (İstanbul Medipol University, 2018)Burn injuries are an incident that can have serious traumatic consequences. Degree of tissue damage depends on height of heat and duration of contact. It can be classified as 4 different burn degrees. Herbal treatments can ... -
Design and characterization of nanocarriers loaded with Levofloxacin for enhanced antimicrobial activity; Physicochemical properties, in vitro release and oral acute toxicity
Siafaka, Panoraia; Okur, Mehmet Evren; Ayla, Şule; Er, Sevda; Çağlar, Emre Şefik; Okur, Neslihan Üstündağ (Faculdade de Ciencias Farmaceuticas (Biblioteca), 2019)Inorganic and carbon based nanomaterials are widely used against several diseases, such as cancer, autoimmune diseases as well as fungi and bacteria colonization. In this work, Santa Barbara Amorphous mesoporous silica ... -
Formulation of microemulsions for dermal delivery of Cephalexin
Üstündağ Okur, Neslihan; Er, Sevda; Çağlar, Emre Şefik; Ekmen, Tarık Ziya; Sala, Furkan (University of Istanbul, 2017)Introduction: Cephalexin monohydrate (CEM) is mostly used because of its activity against both the gram-positive and gram-negative microorganisms for infections. Microemulsions offer numerous advantages for dermal delivery ... -
A novel approach for skin infections: Controlled release topical mats of poly (lactic acid)/poly(ethylene succinate) blends containing Voriconazole
Üstündağ Okur, Neslihan; Filippousi, Maria; Okur, Mehmet Evren; Ayla, Şule; Çağlar, Emre Şefik; Yoltaş, Ayşegül; Siafaka, Panoraia I (Elsevier Science Bv, 2018)The oral and injectable formulations of Voriconazole (VRZ), a known antifungal agent with low solubility, seem to cause severe side effects. Consequently, topical application of VRZ could be advantageous for skin fungal ... -
A novel approach in the treatment of osteoarthritis: In vitro and in vivo evaluation of Allium sativum microemulsion
Okur, Mehmet Evren; Kolbaşı, Bircan; Şahin, Mustafa; Karadağ, Ayşe Esra; Reis, Rengin; Çağlar, Emre Şefik; Kaplan, Arife Ahsen; Sipahi, Hande; Keskin, İlknur; Demiralp, Bahtiyar; Üstündağ Okur, Neslihan (Wiley, 2022)Osteoarthritis (OA) is the most prevalent kind of joint disease, affecting millions of individuals worldwide. Allium sativum L. was used as a therapeutic agent in the microemulsion system against osteoarthritis due to ... -
Phytochemical compounds loaded to nanocarriers as potential therapeutic substances for alzheimer’s disease-could they be effective?
Polat, Derya Çiçek; Karadağ, Ayşe Esra; Parlar Köprülü, Rabia Edibe; Karantas, Ioannis D.; Mutlu, Gökçe; Çağlar, Emre Şefik; Okur, Mehmet Evren; Üstündağ Okur, Neslihan; Siafaka, Panoraia I. (Bentham Science Publishers, 2022)Alzheimer's disease accounts for a high percentage of dementia cases in elderly individuals. This type of brain disease is caused by damage to the brain cells affecting the ability of the patients to communicate, as well ... -
Preparation and evaluation of novel microemulsion-based hydrogels for dermal delivery of benzocaine
Üstündağ Okur, Neslihan; Çağlar, Emre Şefik; Arpa, Muhammet Davut; Karasulu, Hatice Yeşim (Taylor & Francis Ltd, 2017)The purpose of the current research was to prepare and evaluate the potential use of microemulsion-based hydrogel (MBH) formulations for dermal delivery of benzocaine (BZN). The pseudoternary-phase diagrams were constructed ... -
Preparation, optimization and in vivo anti-inflammatory evaluation of hydroquinone loaded microemulsion formulations for melasma treatment
Üstündaǧ Okur, Neslihan; Çağlar, Emre Şefik; Pekcan, Ahmet Nezihi; Okur, Mehmet Evren; Ayla, Şule (Marmara University, 2019)The aim of the study is to evaluate the strengthening of penetration of the epidermis through the formulas containing hydroquinone in melasma treatment and development of alternative new carrier systems. During preparation ... -
Protein and gene delivery systems for neurodegenerative disorders: Where do we stand today?
Siafaka, Panoraia I.; Okur, Mehmet Evren; Dilsiz Erim, Pelin; Çağlar, Emre Şefik; Özgenç, Emre; Gündoğdu, Evren; Parlar Köprülü, Rabia Edibe; Karantaş, Ioannis D.; Üstündağ Okur, Neslihan (MDPI, 2022)It has been estimated that every year, millions of people are affected by neurodegenerative disorders, which complicate their lives and their caregivers’ lives. To date, there has not been an approved pharmacological ...
