Konu "Ubiquitin" için listeleme
Toplam kayıt 2, listelenen: 1-2
-
Evidence that melatonin downregulates Nedd4-1 E3 ligase and its role in cellular survival
(Academic Press Inc Elsevier Science, 2019)Indolamine melatonin structurally resembles non-covalent proteasome inhibitors; however, the role of ubiquitin proteasome system (UPS) in neuronal survival and how melatonin carries out UPS inhibition remain largely unknown. ... -
A proteomic analysis of p53-independent induction of apoptosis by bortezomib in 4T1 breast cancer cell line
(Elsevier Science, 2015)The 26S proteasome is a proteolytic enzyme found in both cytoplasm and nucleus. In this study, we examined the differential expression of proteasome inhibitor bortezomib-induced proteins in p53-deficient 4T1 cells. It was ...