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CD4(+) T cells of myasthenia gravis patients are characterized by ıncreased IL-21, IL-4, and IL-17A productions and higher presence of PD-1 and ICOS
Çebi, Merve; Durmuş, Hacer; Aysal, Fikret; Özkan, Berker; Engin Gül, Gizem; Çakar, Arman; Hocaoğlu, Mehmet; Mercan, Metin; Yentur, Sibel Penbe; Tütüncü, Melih; Yayla, Vildan; Akan, Onur; Doğan, Öner; Parman, Yeşim; Saruhan-Direskeneli, Güher (Frontiers Media SA, 2020)Myasthenia gravis (MG) is an autoimmune disease mediated by autoantibodies predominantly against the acetylcholine receptor (AChR). Specific T cell subsets are required for long-term antibody responses, and cytokines ... -
Correlation between disability status and quality of life in multiple sclerosis female patients with urinary incontinence
Ersin, Aybüke; Alökten, Merve; Mutluay, Fatma; Tütüncü, Melih; Uygunoğlu, Uğur; Saip, Sabahattin; Siva, Aksel (Kartal Dr. Lütfi Kırdar Training and Research Hospital, 2021)Objective: Multiple sclerosis (MS) is a progressive, inflammatory, chronic, and neurodegenerative disease. One of the most common symptoms of MS patients is urinary incontinence with high rates of up to 90%. The previous ...