Yazar "Santella, Regina M." için listeleme
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High levels of global genome methylation in patients with retinoblastoma
Yazıcı, Hülya; Wu, Hui-Chen; Tığlı, Hülya; Yılmaz, Elif Zeynep; Kebudi, Rejin; Santella, Regina M. (Spandidos Publications, 2020)Retinoblastoma is a tumor of the embryonic neural retina in young children. The DNA methyltransferase 1 (DNMT1) gene has been demonstrated to be transcriptionally activated in cells lacking retinoblastoma 1 (RB1). Thus, ...