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Chemical characterization and biological properties of oyster and shiitake mushrooms extracts and their liposomal formulations
In recent years, the production of liposomal formulations using mushroom extracts has gained increasing interest to increase the bioavailability of bioactive compounds in the nutraceutical field. Based on this information, ... -
Formulation development of liposomal coffee extracts and investigation of their antioxidant capacities
Macit, Meltem; Eyüpoğlu, Ozan Emre; Macit, Çağlar; Duman, Gülengül (Elsevier, 2021)he main objective of this study was to carry out the antioxidant capacity of a liposomal formulation either green coffee extract (GCE) and medium roasted coffee extract (RCE) in aq. and MeOH. First, the coffee beans were ... -
Formulation development of Silybum marianum seed extracts and silymarin nanoparticles, and evaluation of hepatoprotective effect
Macit, Meltem; Duman, Gülengül; Cumbul, Alev; Sümer, Engin; Macit, Çağlar (Editions de Sante, 2023)In this study, we formulated silymarin-nanoparticles and assayed their ability to reduce acetaminophen-induced toxicity in vitro and in vivo. After silymarin molecules were encapsulated the loading efficiency and the ... -
Steam bath, vibration, and thermal ablation administrations augment the release of tramadol HCl from transdermal patch and enhance the plasma concentration in rats
Macit, Çağlar; Duman, Gülengül; Macit, Meltem (Marmara University, 2023)Recently, transdermal drug delivery has become popular due to their numerous advantages. They offer non-invasive application and eliminate the first-pass metabolism. The skin membrane is sensitive to heat and vibration ...