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Arctium minus metanol ekstresinin çeşitli kanser hücre hatları üzerinde sitotoksik etkileri
(Ankara Üniversitesi, 2022)Amaç: Bu çalışmada Arctium minus (Hill) Bernh. ssp. minus’un toprak üstü kısımlarından elde edilen metanol ekstresinin kanser hücre hatları üzerindeki sitotoksik etkilerinin değerlendirilmesi amaçlanmıştır. Gereç ve ... -
Are biological agents toxic to human chondrocytes and osteocytes?
(BioMed Central, 2015)Purpose: The aim of the present study is to investigate the effects of biological agents (BAs) on human chondrocytes and osteocytes in vitro. Methods: Primary cell cultures obtained from gonarthrosis patients were divided ... -
Are chondrocytes damaged when rheumatologic inflammation is suppressed?
(Taylor & Francis Inc, 2017)Aim: The use of biological agents (BAs) for treating diseases such as rheumatoid arthritis (RA), spondyloarthropathy, and systemic lupus erythematosus to reduce inflammation has been fruitful. Especially as part of the ... -
Are dentin posts biomechanically intensive?: A laboratory and FEA study
(Taylor & Francis, 2014)The goal of this laboratory and finite elemental stress analysis (FEA) study was to compare fracture strength of dentin post (DP) with stainless steel and glass fiber posts. Single-rooted teeth were decoronated and restored ... -
Are diagnostic magnetic resonance patterns life-saving in children with biotin-thiamine-responsive basal ganglia disease?
(Elsevier Sci Ltd, 2018)Background: Biotin-thiamine responsive basal ganglia disease (BTBGD) is an autosomal recessive disorder caused by mutations in the SLC19A3 gene and characterized by recurrent sub-acute episodes of encephalopathy that ... -
Are Fetuin-A levels beneficial for estimating timing of sepsis occurrence?
(Saudi Medical Journal, 2018)Objectives: To evaluated Fetuin-A levels of patients admitted in the intensive care unit with a diagnosis of sepsis. Methods: This study was conducted at the Faculty of Medicine, Canakkale Onsekiz Mart University Hospital, ... -
Are intervertebral disc tissue cells damaged when attempting to prevent thrombus formation using dabigatran, a new oral anticoagulant?
(Turkish Neurosurgical Society, 2019)AIM: To investigate the effect of dabigatran, a new oral anticoagulant, on human primary cell cultures isolated from intact intervertebral disc tissue. MATERIAL and METHODS: Cell cultures were prepared from tissues obtained ... -
Are oropharyngeal exercises effective in obstructive sleep apnea syndrome?
(IOS Press, 2020)OBJECTIVE: This study has been conducted to examine the effects of posture, cervical region and oropharyngeal exercises in patients with Obstructive Sleep Apnea Syndrome (OSAS). METHOD: Thirty patients with OSAS have been ... -
Are perioperative near-infrared spectroscopy values correlated with clinical and biochemical parameters in cyanotic and acyanotic infants following corrective cardiac surgery?
(Sage Publications Ltd, 2016)Background: Near-infrared spectroscopy (NIRS) is a useful non-invasive tool for monitoring infants undergoing cardiac surgery. In this study, we aimed to determine the NIRS values in cyanotic and acyanotic patients who ... -
Are pretreatment inflammation-based prognostic scores useful in predicting the outcomes of patients with ALK-positive NSCLC?
(Elsevier Science, 2019)Background: Approximately 5% of all diagnosed non-small cell lung cancer (NSCLC) patients harbor a genetic rearrangement between the ALK and EML4 genes, representing a specific molecular and clinical subgroup (ALK+ NSCLC). ... -
Are radio-contrast agents commonly used in discography toxic to the intact intervertebral disc tissue cells?
(Wiley, 2019)In the literature, there have been no studies showing clear results on how radio-contrast pharmaceuticals would affect intact disc tissue cells. In this context, it was aimed to evaluate the effects of iopromide and gadoxetic ... -
Are soluble IL-2 receptor and IL-12p40 levels useful markers for diagnosis of tuberculous pleurisy?
(Taylor & Francis, 2015)Background: The differential diagnostic utilities of the levels of soluble interleukin (IL)-12p40 and the IL-2 receptor in sera and pleural effusions were evaluated in patients with exudative pleural effusions. Methods: ... -
Are specific gene expressions of extracellular matrix and nucleus pulposus affected by primary cell cultures prepared from intact or degenerative intervertebral disc tissues?
(Turkish Neurosurgical Society, 2019)AIM: To determine the gene expression patterns of nucleus pulposus (NP) in cell cultures obtained from degenerated or intact tissues. MATERIAL and METHODS: Whereas 12 of the cases were diagnosed with lumbar disc herniation ... -
Are the functional movement analysis scores of handball players related to athletic parameters?
(Korean Society Exercise Rehabilitation, 2018)Handball is a popular sport in many countries. There is lack of knowledge about handball athlete's functional movement capacity. The aim of this study is to investigate the Functional Movement Screen (EMS) scores, to ... -
Are the leading drugs against Staphylococcus aureus really toxic to cartilage?
(Elsevier Ltd, 2016)Many studies have shown that the toxic effects of local antibiotics on bone and cartilage limit orthopedic surgeons. In this study, we evaluated three antibacterial agents used locally to treat highly mortal and morbid ... -
Are there any new reliable markers to detect renal injury in obese children?
(Taylor & Francis Ltd, 2018)Aim: The aim of this study was to examine the serum and urine levels of kidney injury molecule-1 (KIM-1), neutrophil gelatinase-associated lipocalin (NGAL), osteopontin (OPN), matrix metalloproteinase-9 (MMP-9), and serum ... -
Are there consistent abnormalities in event-related EEG oscillations in patients with Alzheimer's disease compared to other diseases belonging to dementia?
(John Wiley and Sons Inc, 2022)Cerebrospinal and structural-molecular neuroimaging in-vivo biomarkers are recommended for diagnostic purposes in Alzheimer’s disease (AD) and other dementias; however, they do not explain the effects of AD neuropathology ... -
Are we economically efficient enough to ıncrease the potential of in vitro proliferation of osteoblasts by means of pharmacochemical agents?
(Bentham Open, 2016)Background: The aim of this study was to test the necessity of using expensive and unaccesible pharmacological-chemical agents in the proliferation of bone tissue cultures and in the induction of mineralized matrix formation ... -
Are we using slow-acting symptomatic chondroprotective drugs conscious enough?
(Bentham Open, 2017)Background: Osteochondral injuries constitute an entity that is widespread and can be seen in patients of all ages. Actual treatment modalities aim to relieve pain, obtain full range of movement of the joint, and improve ...
