Yazar "Yuluğ, Burak" için listeleme
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The effect of resveratrol on sphingosine-1 and oxidative/ nitrosative stress in an experimental heart ischemia reperfusion model
Avnioğlu, Seda; Güngör, Meltem; Kurutaş, Ergül; Öztürk, Ünal; Demirhan, İlter; Bakariş, Sevgi; Velioğlu, Halil Aziz; Çankaya, Şeyda; Yuluğ, Burak (University Press, 2022)Objectives: Resveratrol (RSV) is a natural polyphenolic compound showing significant antioxidant effects. In this study, we aimed to investigate the effects of resveratrol on the sphingosine-1-phosphate (S1P) and oxidative ... -
The effect of rifampicin on the neuronal cell survival in primary cortical neuron culture after laser axotomy
Ozansoy, Mehmet; Coşkun, Ebru; Ozansoy, Muzaffer Beyza; Çankaya, Şeyda; Günal, Mehmet Yalçın; Bayraktaroğlu, Zübeyir; Yuluğ, Burak; Hanoğlu, Lütfü (2019)Aim: Neurodegeneration caused by the axonal injury is a widely seen phenomenon in spinal cord and traumatic brain injuries. Due to the disintegration of the synaptic connection neurotrophic factors could not be transported ... -
EGb 761 reduces Ca2+ influx and apoptosis after pentylenetetrazole treatment in a neuroblastoma cell line
Övey, İshak Suat; Özşimşek, Ahmet; Velioğlu, Halil Aziz; Altay, Özlem; Mardinoğlu, Adil; Yuluğ, Burak (Frontiers Media SA, 2023)Background: Transient receptor potential (TRP) channels have been found to have significant implications in neuronal outgrowth, survival, inflammatory neurogenic pain, and various epileptogenic processes. Moreover, there ... -
FDG-PET scanning shows distributed changes in cortical activity associated with visual hallucinations in eye disease
Hanoğlu, Lütfü; Yıldız, Sultan; Çakır, Tansel; Hanoğlu, Taha; Yuluğ, Burak (Bentham Science Publ Ltd, 2019)Background and Objective: Charles Bonnet Syndrome (CBS) has been defined as complex visual hallucinations (CVH) due to visual loss. The underlying mechanism of CBS is not clear and the underlying pathophysiology of the ... -
Focused ultrasound and NXY-059 in experimental cerebral ischemia: A new therapeutic opportunity?
Yuluğ, Burak; Hanoğlu, Lütfü; Yamaner, Feysel Yalçın; Kılıç, Ertuğrul; Schabitz, Wolf Rudiger (Bentham Science Publishers, 2016)troke is the third leading cause of morbidity and mortality worldwide. Many deleterious cellular pathways have been proposed to explain the molecular pathogenesis of this clinically devastating disease [1, 2]. The ... -
The functional role of the pulvinar in discriminating between objective and subjective cognitive impairment in major depressive disorder
Yuluğ, Burak; Ayyıldız, Sevilay; Sayman, Dila; Karaca, Ramazan; İpek, Lütfiye; Çankaya, Şeyda; Salar, Ali Behram; Ayyıldız, Behçet; Mikuta, Christian; Yağcı, Nilay; Özdemir Öktem, Ece; Özşimşek, Ahmet; Velioğlu, Halil Aziz; Hanoğlu, Lütfü (John Wiley and Sons Inc, 2024)INTRODUCTIONEmotionally driven cognitive complaints represent a major diagnostic challenge for clinicians and indicate the importance of objective confirmation of the accuracy of depressive patients' descriptions of their ... -
Infection with COVID-19 is no longer a public emergency: But what about degenerative dementia?
Yuluğ, Burak; Ayyıldız, Behçet; Ayyıldız, Sevilay; Sayman, Dila; Salar, Ali Behram; Çankaya, Şeyda; Özdemir, Ece; Özşimşek, Ahmet; Kurt, Çağla Ceren; Lakadamyalı, Hatice; Aktürk, Aynur; Altay, Özlem; Hanoğlu, Lütfü; Velioğlu, Halil Aziz; Mardinoğlu, Adil (John Wiley and Sons Inc, 2023)Although no longer considered a public health threat, post-COVID cognitive syndrome continues to impact on a considerable proportion of individuals who were infected with COVID-19. Recent studies have also suggested that ... -
İn vitro aksotomi modelinde minosiklinin nörorejenerasyona etkisinin araştırılması
Alökten, Merve (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2018)Minosiklin yüksek lipofilik özelliğe sahip, kan beyin bariyerini geçebilen küçük semisentetik tetrasiklinler grubundan bir moleküldür. Antibiyotik özelliğinin yanısıra kan beyin bariyerini geçebilme özelliğinin yardımıyla ... -
Left lateral parietal rTMS improves cognition and modulates resting brain connectivity in patients with Alzheimer's disease: Possible role of BDNF and oxidative stress
Velioğlu, Halil Aziz; Hanoğlu, Lütfü; Bayraktaroğlu, Zübeyir; Toprak, Güven; Güler, Eray Metin; Bektay, Muhammed Yunus; Mutlu Burnaz, Özlem; Yuluğ, Burak (Academic Press Inc., 2021)Repetitive Transcranial Magnetic Stimulation (rTMS) is a non-invasive neuromodulation technique which is increasingly used for cognitive impairment in Alzheimer?s Disease (AD). Although rTMS has been shown to modify ... -
Lhermitte-Duclos disease with orthostatic hypotension
Helvacı Yılmaz, Nesrin; Şeker, Mehmet; Omaygenç, Mehmet Onur; Yaka, Umut; Eryiğit, Nazan; Yuluğ, Burak (Turkish Neurological Society, 2016)Lhermitte-Duclos disease is a rare cerebellar dysplastic gangliocytoma. The most common symptoms include headache, nausea, vomiting, blurred vision, and imbalance. The typical appearance on cranial magnetic resonance imaging ... -
Melatonin affects the release of exosomes and tau-content in in vitro amyloid-beta toxicity model
Ozansoy, Mehmet; Ozansoy, Muzaffer Beyza; Yuluğ, Burak; Çankaya, Şeyda; Kılıç, Ertuğrul; Göktekin, Şule; Kılıç, Ülkan (Elsevier Science Ltd., 2020)Background: Recent studies have been revealed that oxidative damage is the main cause of aging and age-related neurodegenerative diseases like Alzheimer's disease (AD). Melatonin is secreted from the pineal gland and its ... -
Minocycline increases in-vitro cortical neuronal cell survival after laser induced axotomy
Yuluğ, Burak; Ozansoy, Mehmet; Alökten, Merve; Çetin Ozansoy, Muzaffer Beyza; Çankaya, Şeyda; Hanoğlu, Lütfü; Kılıç, Ülkan; Kılıç, Ertuğrul (2020)Antibiotic therapies targeting multiple regenerative mechanisms have the potential for neuroprotective effects, but the diversity of experimental strategies and analyses of non-standardised therapeutic trials are challenging. ... -
More evidence for the therapeutic role of pramipexole in upper limb restlessness due to cervical disc pathology?
Yuluğ, Burak; Hanoğlu, Lütfü; Brandmeier, Sema (Bentham Science Publ Ltd, 2018)Background: The causal link between upper limb restlessness and cervical disc prolapsus is still unclear, and the exact role of the spinal cord in the origination of limb restlessness is not yet completely understood. ... -
The multifactorial role of pre-supplementary motor area stimulation in the freezing of gait: An alternative strategy to the classical drug-Target approach
Sarıcaoğlu, Mevhibe; Hanoğlu, Lütfü; Toprak, Güven; Helvacı Yılmaz, Nesrin; Yuluğ, Burak (Bentham Science Publishers, 2022)Introduction: The pre-supplementary motor area (Pre-SMA) plays a pivotal role in the control of voluntary motor control and freezing of gait (FOG) pathophysiological mechanism. Here, we aimed to modulate if the pre-SMA ... -
Neuroimaging-guided transcranial magnetic and direct current stimulation in MCI: Toward an individual, effective and disease-modifying treatment
Hanoğlu, Lütfü; Velioğlu, Halil Aziz; Hanoğlu, Taha; Yuluğ, Burak (SAGE Publications Inc, 2023)The therapeutic approaches currently applied in Alzheimer's disease (AD) and similar neurodegenerative diseases are essentially based on pharmacological strategies. However, despite intensive research, the effectiveness ... -
The neuroprotective effect of focused ultrasound: New perspectives on an old tool
Yuluğ, Burak; Hanoğlu, Lütfü; Kılıç, Ertuğrul (Pergamon-Elsevier Science Ltd., 2017)Introduction Transcranial focused ultrasound (tFUS) is a novel technique that can noninvasively modulate the cortical function. Moreover, there are rapidly replicating evidence suggesting the role of tFUS for targeted ... -
Neuroprotective effect of lithium in cold- induced traumatic brain injury in mice
Çiftci, Elvan; Karaçay, Reyda; Çağlayan, Aysun; Altunay, Serdar; Ateş, Nilay; Altıntaş, Mehmet Özgen; Doeppner, Thorsten Roland; Yuluğ, Burak; Kılıç, Ertuğrul (Elsevier, 2020)Apart from its well-established therapeutic activity on bipolar disorder and depression, lithium exerts neuroprotective activity upon neurodegenerative disorders, such as traumatic brain injury (TBI). However, the cellular ... -
The neuroprotective role of repetitive transcranial magnetic stimulation (rTMS) for neurodegenerative diseases: A short review on experimental studies
Yuluğ, Burak; Hanoğlu, Lütfü; Kılıç, Ertuğrul; Polat, Burcu; Schabitz, Wolf Ruediger (Bentham Science Publishers, 2016)There are rapidly replicating human data suggesting the therapeutic and neurorestorative role of transcranial magnetic stimulation in various neurological and psychiatric disorders. However there are only limited experimental ... -
NTNG2 Mutation: A candidate gene for a new brain-skin disorder with early neuropsychiatric manifestation? An analysis based on 3000 patients
Yuluğ, Burak; Ayaz, Akif (Alanya Alaaddin Keykubat University, 2022)Aim: In this study, the relationship between genetic analysis and exome sequencing and clinical and neuroimaging findings of four patients from the same family was investigated by analyzing a clinical and genetic (WES) ...