Yazar "Baykal, Ahmet Tarık" için listeleme
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A proteomic analysis of p53-independent induction of apoptosis by bortezomib in 4T1 breast cancer cell line
Yerlikaya, Azmi; Okur, Emrah; Baykal, Ahmet Tarık; Acılan, Ceyda; Boyacı, İhsan; Ulukaya, Engin (Elsevier Science, 2015)The 26S proteasome is a proteolytic enzyme found in both cytoplasm and nucleus. In this study, we examined the differential expression of proteasome inhibitor bortezomib-induced proteins in p53-deficient 4T1 cells. It was ... -
Proteomic study of the microdissected aortic media in human thoracic aortic aneurysms
Serhatlı, Müge; Baysal, Kemal; Açılan, Ceyda; Tuncer, Eylem; Bekpınar, Seldağ; Baykal, Ahmet Tarık (American Chemical Society, 2014)Aortic aneurysm is a complex multifactorial disease, and its molecular mechanism is not understood. In thoracic aortic aneurysm (TAA), the expansion of the aortic wall is lead by extracellular matrix (ECM) degeneration in ... -
Proteomics analysis of CA1 region of the hippocampus in pre-, progression and pathological stages in a mouse model of the alzheimer’s disease
Gürel, Büşra; Cansev, Mehmet; Koç, Cansu; Öcalan, Büşra; Çakır, Aysen; Aydın, Sami; Kahveci, Nevzat; Ulus, İsmail Hakkı; Şahin, Betül; Başar, Merve Karayel; Baykal, Ahmet Tarık (Bentham Science Publishers, 2019)Background: CA1 subregion of the hippocampal formation is one of the primarily affected structures in AD, yet not much is known about proteome alterations in the extracellular milieu of this region. Objective: In this ... -
Time-of-day dependent neuronal injury after ischemic stroke: Implication of circadian clock transcriptional factor bmal1 and survival kinase akt
Beker, Mustafa Çağlar; Çağlayan, Berrak; Yalçın, Esra; Çağlayan, Ahmet Burak; Türkseven, Şeyma; Gürel, Büşra; Keleştemur, Taha; Sertel, Elif; Şahin, Zafer; Kutlu, Selim; Kılıç, Ülkan; Baykal, Ahmet Tarık; Kılıç, Ertuğrul (Humana Press Inc, 2018)Occurrence of stroke cases displays a time-of-day variation in human. However, the mechanism linking circadian rhythm to the internal response mechanisms against pathophysiological events after ischemic stroke remained ... -
Yenidoğan alzheimer transgenik fare modelinde farklı beyin bölgelerinde protein profil değişimlerinin incelenmesi
Mazi, Aişe Rümeysa (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2016)Alzheimer Hastalığı (AH), belirgin hafıza kayıplı kortikal demansa sebep olan çeşitli moleküler patolojilerle tanımlanan progresif bir hastalıktır. Hastalığın tanısından onlarca yıl önce oluşmaya başlayan patolojinin ...