Yazar "Ayla, Şule" için listeleme
-
In vivo wound-healing and in vitro antibacterial and antioxidant of Carduus extract
Şakul, Ayşe Arzu; Ayla, Şule; Okur, Mehmet Evren; Karadağ, Ayşe Esra; Daylan, Benay; Güzel, Elif; Özdemir, Ekrem Musa; Günal, Mehmet Yalçın (Marmara University, 2023)Carduus adpressus has been used for its anti-hair loss effect in traditional folk medicine. The plant species is mainly distributed in Turkiye, Bulgaria, and the Western Caucasus. The studies on this specific plant in the ... -
In vivo wound-healing and in vitro antibacterial and antioxidant properties of Carduus adpressus extract
Şakul, Ayşe Arzu; Ayla, Şule; Okur, Mehmet Evren; Karadağ, Ayşe Esra; Daylan, Benay; Güzel, Elif; Özdemir, Ekrem Musa; Günal, Mehmet Yalçın (Marmara University, 2023)Carduus adpressus has been used for its anti-hair loss effect in traditional folk medicine. The plant species is mainly distributed in Türkiye, Bulgaria, and the Western Caucasus. The studies on this specific plant in the ... -
İnsan sperm kriyoprezervasyonunun sperm motilitesi ve deoksiribonükleik asit (DNA) fragmantasyonuna etkisinin leptin molekülü ile ilişkisi
Önel, Tuğçe (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2016)Radyoterapi, kemoterapi ve bazı maligniteler sonucu ejekülatuar disfonksiyon ve testiküler yetmezlik oluşabilir. Bu gibi durumlar için çiftlere çocuk sahibi olma konusunda yardımcı olabilecek metod sperm kriyoprezervasyonudur. ... -
LDH-A inhibitor as a remedy to potentiate the anticancer effect of docetaxel in prostate cancer
Çakıcı, Çağrı; Daylan, Benay; Ünlüer, Rüveyde Safiye; Emekli Alturfan, Ebru; Ayla, Şule; Eren Gözel, Hilal; Yiğit, Pakize; Yavuz Dokgöz, Elif; Yiğitbaşı, Türkan (Ivyspring International Publisher, 2024)Increased LDH-A activity promotes tumor growth, migration, invasion, and metastasis. This study aimed to investigate the effects of the combination of LDH-A inhibitor and Docetaxel on apoptosis and epithelial-mesenchymal ... -
Leptin in sperm analysis can be a new indicator
Önel, Tuğçe; Ayla, Şule; Keskin, İlknur; Parlayan, Cüneyd; Yiğitbaşı, Türkan; Kolbaşı, Bircan; Varlı Yelke, Tuba; Şenel Ustabaş, Tuğba (Elsevier GMBH, 2019)Purpose Radiotherapy, chemotherapy, various tumors and invasive surgery can result in ejaculatory dysfunction and testicular insufficiency. Sperm cryopreservation is the only method which can provide a baby for couples. ... -
Neuroprotective effect of intrastriatal caffeic acid phenethyl ester treatment in 6-oh dopamine model of parkinson's disease in rats
Soner, Burak Cem; Açıkgöz, Eda; İnan, Salim Yalçın; Ayla, Şule; Şahin, Ayşe Saide; Öktem, Gülperi (Hindawi Ltd, 2021)Parkinson's disease (PD) is the second most common neurodegenerative disorder, and the main cause of PD is still not known. Until now, no cure for Parkinson's disease is yet in sight. Caffeic acid phenethyl ester (CAPE) ... -
A novel approach for skin infections: Controlled release topical mats of poly (lactic acid)/poly(ethylene succinate) blends containing Voriconazole
Üstündağ Okur, Neslihan; Filippousi, Maria; Okur, Mehmet Evren; Ayla, Şule; Çağlar, Emre Şefik; Yoltaş, Ayşegül; Siafaka, Panoraia I (Elsevier Science Bv, 2018)The oral and injectable formulations of Voriconazole (VRZ), a known antifungal agent with low solubility, seem to cause severe side effects. Consequently, topical application of VRZ could be advantageous for skin fungal ... -
Novel insight into wound healing properties of methanol extract of Capparis ovata Desf. var. palaestina Zohary fruits
Okur, Mehmet Evren; Ayla, Şule; Polat, Derya Çiçek; Günal, Mehmet Yalçın; Yoltaş, Ayşegül; Biçeroğlu, Özge (Wiley, 2018)ObjectivesThe objective of this study was to investigate the wound healing activity of Capparis ovata var. palaestina fruit extract in mice. For this aim, wound healing, invitro antimicrobial and antioxidant activities, ... -
Opuntia ficus indica fruits ameliorate cisplatin-induced nephrotoxicity in mice
Okur, Mehmet Evren; Ayla, Şule; Karadağ, Ayşe Esra; Polat, Derya Çiçek; Demirci, Sibel; Seçkin, İsmail (Pharmaceutical Society of Japan, 2020)This study aims to determine the potential renal protective effects of Opuntia ficus-indica (L.) Miller (OFI) fruits against cisplatin-induced nephrotoxicity in mice. The antioxidant activity of OH methanol extract was ... -
Preparation and evaluation of QbD based fusidic acid loaded in situ gel formulations for burn wound treatment
Aksu, Neşe Buket; Yozgatlı, Vildan; Okur, Mehmet Evren; Ayla, Şule; Yoltaş, Ayşegül; Üstündağ Okur, Neslihan (Elsevier, 2019)The purpose of this research was to prepare and evaluate the potential use of in situ gel formulations for dermal delivery of fusidic acid for burn wound treatment. Temperature sensitive in situ gels were successfully ... -
Preparation, optimization and in vivo anti-inflammatory evaluation of hydroquinone loaded microemulsion formulations for melasma treatment
Üstündaǧ Okur, Neslihan; Çağlar, Emre Şefik; Pekcan, Ahmet Nezihi; Okur, Mehmet Evren; Ayla, Şule (Marmara University, 2019)The aim of the study is to evaluate the strengthening of penetration of the epidermis through the formulas containing hydroquinone in melasma treatment and development of alternative new carrier systems. During preparation ... -
Prognostic significance of tumor tissue NeuGcGM3 ganglioside expression in patients receiving racotumomab immunotherapy
Üskent, Necdet; Ayla, Şule; Molinas Mandel, Nil; Özkan, Metin; Teomete, Mehmet; Baloğlu, Hüseyin; Aydinçer, Cenk; Yergök, Hale; Doğan, Ender; Berk, Barkın; Yazar, Aziz (Hindawi Ltd., 2020)Expression ofN-glycolyl GM3 (NeuGcGM3) ganglioside was detected in the tumor specimens of patients who were on Racotumomab anti-idiotype vaccine maintenance treatment, and prognostic significance as a biomarker was ... -
Prognostic significance of tumour tissue NeuGcGM3 ganglioside expression and predictive value of circulating tumour cell count monitoring in patients receiving racotumomab immunotherapy
Üskent, Necdet; Ayla, Şule; Mandel, Nil Molinas; Özkan, Metin; Teomete, Mehmet; Baloğlu, Hüseyin; Aydinçer, Cenk; Yergök, H.; Doğan, Erkan; Berk, Barkın; Yazar, Aziz (Oxford University Press, 2019)... -
Promising nanogels loaded with usnic acid for oral ulcer treatment: Development, characterization, and in vivo evaluation in rabbits
Coşkunmeriç, Nesrin; Üstündağ Okur, Neslihan; Okur, Mehmet Evren; Ayla, Şule; Yoltaş, Ayşegül; Karavana, Sinem Yaprak (Taylor and Francis Ltd., 2021)This study aimed to present an effective formulation targeting oral ulcers that will remain in the application site for a longer period, reducing the frequency of administration. As a candidate formulation, usnic acid (UA) ... -
Prunus spinosa L. meyvelerinin deneysel yara iyileşmesi üzerine etkileri
Ayla, Şule; Günal, Mehmet Yalçın; Sayın Şakul, Ayşe Arzu; Biçeroğlu, Özge; Özdemir, Ekrem Musa; Okur, Mehmet Evren; Polat, Derya Çiçek; Üstündağ Okur, Neslihan; Bilgiç, Bülent Emre (2017)Farelerde oluşturduğumuz deneysel yara modellerinde, Prunus Spinosa L. metanollü meyve ekstresini kullanarak, bu ekstrenin yara iyileşmesindeki etkisini araştırdık. Otuz iki adet C57/Black fare ile 4 deney grubu oluşturuldu. ... -
The rate of oocytes with granular cytoplasm is higher in women with endometrioma in ICSI cycles
Bilgiç, Bülent Emre; Kürek Eken, Meryem; Ayla, Şule; Köse, Ayşe; Kutlu, Tayfun; İlhan, Gülşah (Taylor & Francis Inc, 2022)The purpose of this study was to investigate the impact of endometrioma on oocyte morphology and fertility outcome in intracytoplasmic sperm injection (ICSI)cycles. The study material was obtained from 114 ICSI cycles of ... -
Resveratrol can prevent CCl4-induced liver injury by inhibiting notch signaling pathway
Tanrıverdi, Gamze; Kaya Dağiştanlı, Fatma; Ayla, Şule; Demirci, Sibel; Eser, Mediha; Ünal, Zehra Seda; Cengiz, Müjgan; Oktar, Hüseyin (F Hernandez, 2016)We investigated whether Notch signaling was increased in an experimental liver fibrosis model and examined the effects of resveratrol on Notch expression. Rats were divided into four groups: the control group, injected ... -
The rhythmicity of life: A review of the circadian clocks
Açıkgöz, Eda; Karahüseyinoğlu, Serçin; Ayla, Şule; Öktem, Gülperi (Begell House Inc., 2021)Physiology of the mammalian body has been adapted to diurnal cycles of around 24 h, an evolutionary situation that affects a wide spectrum of biological events including sleep-to-wake transitions, feeding/fasting, body ... -
Squalene attenuates the oxidative stress and activates AKT/mTOR pathway against cisplatin-induced kidney damage in mice
Sakul, Arzu; Ozansoy, Mehmet; Elibol, Birsen; Ayla, Şule; Günal, Mehmet Yalçın; Yozgat, Yasemin; Basağa, Hüveyda; Şahin, Kazım; Kazancıoğlu, Rümeyza; Kılıç, Ulkan (Tubitak Scientific & Technical Research Council Turkey, 2019)The clinical use of cisplatin, which is a first-line anticancer agent, is highly restricted due to its adverse effects on kidneys that lead to nephrotoxicity. Therefore, some potential reno-protective substances have been ...