Yazar "Üstündağ Okur, Neslihan" için listeleme
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A novel approach in the treatment of osteoarthritis: In vitro and in vivo evaluation of Allium sativum microemulsion
Okur, Mehmet Evren; Kolbaşı, Bircan; Şahin, Mustafa; Karadağ, Ayşe Esra; Reis, Rengin; Çağlar, Emre Şefik; Kaplan, Arife Ahsen; Sipahi, Hande; Keskin, İlknur; Demiralp, Bahtiyar; Üstündağ Okur, Neslihan (Wiley, 2022)Osteoarthritis (OA) is the most prevalent kind of joint disease, affecting millions of individuals worldwide. Allium sativum L. was used as a therapeutic agent in the microemulsion system against osteoarthritis due to ... -
Novel microemulsion containing benzocaine and fusidic acid simultaneously: Formulation, characterization, and in vitro evaluation for wound healing
Arpa, Muhammet Davut; Çağlar, Emre Şefik; Güreşçi, Dilara; Sipahi, Hande; Üstündağ Okur, Neslihan (Springer Science and Business Media Deutschland GmbH, 2024)Modern drug carrier technologies, such as microemulsions with small droplet sizes and high surface areas, improve the ability of low water solubility active ingredients to permeate and localize. The goal of this study was ... -
Ophthalmic applications of SLN and NLC
Üstündağ Okur, Neslihan; Homan Gökçe, Evren (Bentham Science Publishers Ltd., 2017)Background: The eyes are among the most readily accessible organs in terms of location in the body, yet drug delivery to eye tissues is particularly problematic. The anatomy, physiology and biochemistry of the eye limit ... -
An optimization study on solid lipid nanoparticles using artificial neural network
Yurdasiper, Aysu; Aksu, Buket; Üstündağ Okur, Neslihan; Gökçe, Evren Homan (Colegio Farmaceuticos Provincia De Buenos Aires, 2017)Common use of supportive programs in finding the best in R&D studies provides positive results and thus ensures benefits to companies in terms of cost and time. The aim of this work was to develop, evaluate and optimize ... -
Phytochemical compounds loaded to nanocarriers as potential therapeutic substances for alzheimer’s disease-could they be effective?
Polat, Derya Çiçek; Karadağ, Ayşe Esra; Parlar Köprülü, Rabia Edibe; Karantas, Ioannis D.; Mutlu, Gökçe; Çağlar, Emre Şefik; Okur, Mehmet Evren; Üstündağ Okur, Neslihan; Siafaka, Panoraia I. (Bentham Science Publishers, 2022)Alzheimer's disease accounts for a high percentage of dementia cases in elderly individuals. This type of brain disease is caused by damage to the brain cells affecting the ability of the patients to communicate, as well ... -
Preparation and evaluation of novel microemulsion-based hydrogels for dermal delivery of benzocaine
Üstündağ Okur, Neslihan; Çağlar, Emre Şefik; Arpa, Muhammet Davut; Karasulu, Hatice Yeşim (Taylor & Francis Ltd, 2017)The purpose of the current research was to prepare and evaluate the potential use of microemulsion-based hydrogel (MBH) formulations for dermal delivery of benzocaine (BZN). The pseudoternary-phase diagrams were constructed ... -
Preparation and evaluation of QbD based fusidic acid loaded in situ gel formulations for burn wound treatment
Aksu, Neşe Buket; Yozgatlı, Vildan; Okur, Mehmet Evren; Ayla, Şule; Yoltaş, Ayşegül; Üstündağ Okur, Neslihan (Elsevier, 2019)The purpose of this research was to prepare and evaluate the potential use of in situ gel formulations for dermal delivery of fusidic acid for burn wound treatment. Temperature sensitive in situ gels were successfully ... -
Promising nanogels loaded with usnic acid for oral ulcer treatment: Development, characterization, and in vivo evaluation in rabbits
Coşkunmeriç, Nesrin; Üstündağ Okur, Neslihan; Okur, Mehmet Evren; Ayla, Şule; Yoltaş, Ayşegül; Karavana, Sinem Yaprak (Taylor and Francis Ltd., 2021)This study aimed to present an effective formulation targeting oral ulcers that will remain in the application site for a longer period, reducing the frequency of administration. As a candidate formulation, usnic acid (UA) ... -
Protein and gene delivery systems for neurodegenerative disorders: Where do we stand today?
Siafaka, Panoraia I.; Okur, Mehmet Evren; Dilsiz Erim, Pelin; Çağlar, Emre Şefik; Özgenç, Emre; Gündoğdu, Evren; Parlar Köprülü, Rabia Edibe; Karantaş, Ioannis D.; Üstündağ Okur, Neslihan (MDPI, 2022)It has been estimated that every year, millions of people are affected by neurodegenerative disorders, which complicate their lives and their caregivers’ lives. To date, there has not been an approved pharmacological ... -
Prunus spinosa L. meyvelerinin deneysel yara iyileşmesi üzerine etkileri
Ayla, Şule; Günal, Mehmet Yalçın; Sayın Şakul, Ayşe Arzu; Biçeroğlu, Özge; Özdemir, Ekrem Musa; Okur, Mehmet Evren; Polat, Derya Çiçek; Üstündağ Okur, Neslihan; Bilgiç, Bülent Emre (2017)Farelerde oluşturduğumuz deneysel yara modellerinde, Prunus Spinosa L. metanollü meyve ekstresini kullanarak, bu ekstrenin yara iyileşmesindeki etkisini araştırdık. Otuz iki adet C57/Black fare ile 4 deney grubu oluşturuldu. ... -
Quality by design approach for optimizing preparation and characterization of buccal film formulation with different polymers
Aksu, Buket; Coşkunmeriç, Nesrin; Yeğen, Gizem; Özalp, Yıldız; Üstündağ Okur, Neslihan (Advanced Scientific Research, 2019)Bilayered oromucosal film preparations (buccal films) offer a promising way to enable drug administration via the oral cavity. Polymeric film formulations containing chitosan, sodium alginate or carbopol were evaluated to ... -
Rosmarinus officinalis L. essential oil encapsulated in new microemulsion formulations for enhanced antimicrobial activity
Karadağ, Ayşe Esra; Üstündağ Okur, Neslihan; Demirci, Betül; Demirci, Fatih (Wiley, 2022)In this present study, Rosmarinus officinalis essential oil and its new microemulsions (MEs) were evaluated both for the in vitro antibacterial and antifungal activity. The essential oil composition was verified initially ...