Yazar "Yılmaz, İbrahim" için listeleme
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Effect of naproxen on proliferation and differentiation of primary cell cultures isolated from human cartilage tissue
Karaarslan, Numan; Batmaz, Ahmet Güray; Yılmaz, İbrahim; Özbek, Hanefi; Çalışkan, Tezcan; Yaşar Şirin, Duygu; Kaplan, Necati; Öznam, Kadir; Ateş, Özkan (Spandidos Publications Ltd, 2018)Non-steroidal anti-inflammatory drugs (NSAIDs) that are applied through oral, injectable or topical routes have been widely used in painful and inflammatory musculoskeletal diseases. The current study aimed to determine ... -
Effects of etanercept, a tumor necrosis factor receptor fusion protein, on primary cell cultures prepared from intact human intervertebral disc tissue
Çalışkan, Tezcan; Şirin, Duygu Yaşar; Karaarslan, Numan; Yılmaz, İbrahim; Özbek, Hanefi; Akyuva, Yener; Kaplan, Necati; Kaya, Yasin Emre; Şimşek, Abdullah Talha; Güzelant, Aliye Yıldırım; Ateş, Özkan (Spandidos Publications, 2019)The aim of the present study was to investigate the effects of etanercept (ETA), a tumor necrosis factor (TNF) inhibitor, on human cell cultures prepared from intact intervertebral disc tissue. ETA is used as a treatment ... -
The effects of NLR on the diagnosis and pharmacological management of brain abscesses
Çalışkan, Tezcan; Yılmaz, İbrahim; Hacıoğlu Kasım, Fatma Bahar; Ersöz, Emel; Doğan, Mustafa; Karaaslan, Numan (Alanya Alaaddin Keykubat University, 2021)Aim: The present study aims to examine the effectiveness of the neutrophil-tolymphocyte ratio in the treatment and diagnosis of patients with brain abscesses. Methods: In this retrospective study, radiological, neurological, ... -
The effects of rivaroxaban, an oral anticoagulant, on human IVD primary cultures
Çalışkan, Tezcan; Akalan, Hande; Yılmaz, İbrahim; Karaarslan, Numan; Yaşar Şirin, Duygu; Özbek, Hanefi (Termedia Publishing House Ltd, 2022)Introduction: The present study aimed to investigate the potential effects of rivaroxaban, an oral anticoagulant that inhibits the effects of factor Xa, on intact intervertebral disc tissue cells and the extracellular ... -
Empathy and facial expression recognition in children with and without attention-deficit/hyperactivity disorder: Effects of stimulant medication on empathic skills in children with attention-deficit/hyperactivity disorder
Gümüştaş, Funda; Yılmaz, İbrahim; Yulaf, Yasemin; Gökçe, Sebla; Sabuncuoğlu, Osman (Mary Ann Liebert, Inc, 2017)Objective: The aim of this study was to compare children and adolescents with attention-deficit/hyperactivity disorder (ADHD) to healthy children and adolescents in terms of state and trait empathy and emotion expression ... -
Evaluation of antibiotic alternatives used in orthopedic departments of 2 hospitals according to rational use of antibiotics
İşyar, Mehmet; Doğan, Mustafa; Gümüştaş, Seyit Ali; Yılmaz, İbrahim; Bilir, Bülent; Güler, Olcay; Saraçoğlu Varol, Gamze; Mahiroğulları, Mahir (Kare Yayıncılık ve İletişim Hizmetleri, 2016)Background: The present study is an analysis of appropriateness of antibiotics use for patients in whom infectious agent was detected. Data from patients in orthopedics and traumatology department of 2 hospitals in the ... -
Evaluation of empirical antibiotic treatment in culture negative pyogenic vertebral osteomyelitis
Doğan, Mustafa; Şimşek, Abdullah Talha; Yılmaz, İbrahim; Karaarslan, Numan (Turkish Neurosurgical Society, 2019)AIM: To investigate the efficacy of empirical antibiotic treatment in culture-negative pyogenic vertebral osteomyelitis (PVO) cases. MATERIAL and METHODS: The records of patients with culture-negative PVO who were treated ... -
Evaluation of neutrophil-to-lymphocyte ratio as a marker of inflammatory response in septic arthritis
Bilir, Bülent; İşyar, Mehmet; Yılmaz, İbrahim; Saraçoǧlu, Gamze Varol; Çakmak, Selami; Doǧan, Mustafa; Mahiroğulları, Mahir (Sage Publications, 2015)Is neutrophil-to-lymphocyte ratio high in patients with septic arthritis? Septic arthritis may lead to higher rates of morbidity or even mortality if not diagnosed on time. This study was planned to answer the question ... -
Evaluation of neutrophil-to-lymphocyte ratio as a marker of inflammatory response in spondylodiscitis
Karaarslan, Numan; Yılmaz, İbrahim; Akgün, Feride Sinem; Çalıskan, Tezcan; Doğan, Mustafa; Bilir, Bülent; Ateş, Özkan (2018)Aim: Spondylodiscitis, if not diagnosed on time, can cause morbidity or mortality at high rates. This study was carried out with the aim of testing the hypothesis that “neutrophil-to-lymphocyte ratio can be used” especially ... -
Evaluation of the effect of apixaban on the primary intact intervertebral disc cell cultures
Akgün, Feride Sinem; Karaarslan, Numan; Yılmaz, İbrahim; Özbek, Hanefi; Yaşar Şirin, Duygu; Şimşek, Abdullah Talha; Kaplan, Necati; Ateş, Özkan (2019)Aim: Apixaban is a frequently preferred pharmacological agent in clinics to prevent deep vein thrombosis and pulmonary embolism.Such new oral anticoagulants may cause hemorrhage’s in tissues and/or organs or may cause ... -
Evaluation of the effect of daptomycin, a glycopeptide agent, on intact intervertebral disc tissue
Kaplan, Necati; Yılmaz, İbrahim; Karaaslan, Numan; Yaşar Şirin, Duygu; Şimşek, Abdullah Talha; Çalışkan, Tezcan; Bircan, Rıfat; Özbek, Hanefi (Turkish Neurosurgical Society, 2019)AIM: To evaluate the effects of pre- and intra-operatively administered daptomycin (DAP) on the intact human primary intervertebral disc tissue cells. MATERIAL and METHODS: Primary cell cultures were established using ... -
Evaluation of the expression and proliferation of degenerative markers in primary cell cultures obtained from human intervertebral disc tissue
Kaya, Yasin Emre; Akalan, Hande; Yılmaz, İbrahim; Karaarslan, Numan; Yaşar Şirin, Duygu; Özbek, Hanefi (Annals of Medical Research Publishing Inc, 2020)Aim: A major cause of low back pain is disc degeneration. Nevertheless, no specific and reliable markers of the degeneration of the nucleus pulposus (NP) are available. This presented study aimed to examine changes in the ... -
In-vitro evaluation of the effects of tigecycline on annulus firosus and nucleus pulposus
Kaya, Yasin Emre; Yılmaz, İbrahim; Karaarslan, Numan; Bilir, Bülent; Yaşar Şirin, Duygu; Özbek, Hanefi (Annals of Medical Research Publishing Inc, 2020)Aim: This study aimed to examine the effects of tigecycline on primary cell cultures established using intervertebral disc tissues. Material and Methods: Primary Annulus Fibrosus and Nucleus Pulposus cultures were obtained ... -
An interval-valued pythagorean fuzzy AHP and COPRAS hybrid methods for the supplier selection problem
Erdebilli, Babek; Yılmaz, İbrahim; Aksoy, Tamer; Hacıoğlu, Ümit; Yüksel, Serhat; Dinçer, Hasan (Springer Nature, 2023)Companies must be able to identify their suppliers appropriately and effectively in order to survive in the competitive market conditions. In order to fulfill and surpass the expectations of the consumers and clients, ... -
Investigation of the effect of dipyrone on cells isolated from intervertebral disc tissue
Akgün, Feride Sinem; Şirin, Duygu Yaşar; Yılmaz, İbrahim; Karaarslan, Numan; Özbek, Hanefi; Şimşek, Abdullah Talha; Kaya, Yasin Emre; Kaplan, Necati; Akyuva, Yener; Çalışkan, Tezcan; Ateş, Özkan (Spandidos Publications, 2019)The present study aimed to evaluate the effects of dipyrone, an indispensable analgesic, anti-pyretic and anti-spasmodic used in emergency departments, on nucleus pulposus and annulus fibrosus cells in vitro. After surgical ... -
Investigation of the effects of methylphenidate, an amphetamine derivative, on intervertebral disc tissue cell cultures and matrix structures
Kaya, Yasin Emre; Karaarslan, Numan; Şirin, Duygu Yaşar; Özbek, Hanefi; Kaplan, Necati; Yılmaz, İbrahim (Turkish Neurosurgical Society, 2019)AIM: To investigate the effects of methylphenidate (MPH), on intervertebral disc tissue (IVD) cell cultures and extracellular matrix structures. Changes in the expression of some important marker genes involved in anabolic ... -
Investigation of the effects of tigecycline, a semi-synthetic derivative of minocycline, on chondrocyte cultures
Kaya, Yasin Emre; Karaarslan, Numan; Yılmaz, İbrahim; Yaşar Şirin, Duygu; Yaman, Onur; Özbek, Hanefi; Ateş, Özkan (Annals of Medical Research Publishing Inc, 2020)Abstract Aim: Although antibiotics are generally well-tolerated, they may have cytotoxic effects. The present randomized, double-blind, in vitro study aimed to investigate the effects of tigecycline on cartilage tissue ... -
Iopromide- and gadopentetic acid-derived preparates used in MR arthrography may be harmful to chondrocytes
Öznam, Kadir; Şirin, Duygu Yaşar; Yılmaz, İbrahim; Kaya, Yasin Emre; İşyar, Mehmet; Gümüştaş, Seyit Ali; Özbek, Hanefi; Akkaya, Semih; Kayhan, Arda; Mahiroğulları, Mahir (BMC, 2017)Background: Magnetic resonance arthrography, a procedure through which contrast agents containing gadolinium and/or iopromide are administered intra-articularly, has become a useful tool in musculoskeletal diagnosis. ... -
Is implant washing and wound irrigation with rifampicin effective for preventing surgical site infections in lumbar instrumentation?
Karaarslan, Numan; Yılmaz, İbrahim; Özbek, Hanefi; Öznam, Kadir; Ateş, Özkan; Erdem, İlknur (Turkish Neurosurgical Society, 2018)AIM: To determine whether the washing of implants and autogenous bone grafts with rifampicin, and the irrigation of the surgical field using diluted rifampicin, have any significant effect on the prevention of spinal implant ... -
Is it possible to treat osteosarcoma using oligonucleotides confined into controlled release drug delivery systems?
Topuk, Savaş; Akyuva, Yener; Karaaslan, Numan; Mutlu, Çağri Ata; Yılmaz, İbrahim; İşyar, Mehmet; Şirin, Duygu Yaşar; Akkaya, Semih; Özbek, Hanefi; Mahiroğulları, Mahir (Bentham Science Publishers Ltd, 2017)Purpose: The present study aimed to analyze the researches that are at the experimental phase concerning osteosarcoma treatment. The researches included drug delivery systems which allow controlled release and imbue small ...