Balaban, Yasemin HaticeŞimşek, HalisTatar, Gonca10.07.20192019-07-1010.07.20192019-07-102014Balaban, Y. H., Şimşek, H. ve Tatar, G. (2014). Gastric cancer prevention from the point of helicobacter. Turkish Journal of Gastroenterology, 25(4), 463-467. https://dx.doi.org/10.5152/tjg.2014.81121300-4948https://dx.doi.org/10.5152/tjg.2014.8112https://hdl.handle.net/20.500.12511/3934WOS: 000345025900038PubMed ID: 25254545When the first cancer estimates of world were made in 1975, gastric cancer (GC) was the most common neoplasm, making 70% of the total. Although its rate decreased to 6.8% in 2012, it is still the fifth most common malignancy after cancers of the lung, breast, colo-rectum, and prostate and the third leading cause of cancer death in both sexes worldwide (8.8%, 723,000 deaths) (1). Proximal (cardia) and distal (non-cardia) gastric adenocarcinomas have different epidemiological and clinical features. Although there is an increase in proximal GCs, most of the GCs are still distally located, and intestinal-type. H. pylori is an established trigger of gastric carcinogenesis; reversibility of precancerous conditions, including intestinal metaplasia (IM), after eradication treatment is a hot topic for research. Therefore, we read with great interest the study by Galiatsatos P et al. (2) on the sensitivity of gastric biopsy for H. pylori detection in the presence of IM. The data have once again emphasized the importance of using non-invasive tests and histopathology together in the presence of gastric IM.eninfo:eu-repo/semantics/openAccessGastric CancerHelicobacterLetter25446346710.5152/tjg.2014.8112Q4Q3