Gündoğdu-Karaburun, NalanKaraburun, Ahmet ÇağrıDemirayak, ŞerefKayagil, İsmailYurttaş, Leyla10.07.20192019-07-1010.07.20192019-07-102014Gündoğdu-Karaburun, N., Karaburun, A. Ç., Demirayak, Ş., Kayagil, İ. ve Yurttaş, L. (2014). Synthesis and anticancer activity of some 2-[3/4-(2-substituted phenyl-2-oxoethoxy)benzylidene]-6-substituted-2,3-dihydro-1H-inden-1-one derivatives. Letters in Drug Design & Discovery, 11(5), 578-585. https://dx.doi.org/10.2174/15701808116661404030012121570-18081875-628Xhttps://dx.doi.org/10.2174/1570180811666140403001212https://hdl.handle.net/20.500.12511/3383WOS: 000335394500005The synthesis of 2-[3/ 4-(2-substituted phenyl-2-oxoethoxy) benzylidene]-6-substituted-2,3-dihydro-1H-inden-1one derivatives and the investigation of their anticancer activity were studied. 2-(3- or 4-Hydroxybenzylidene)-6substituted- 2,3-dihydro-1H-inden-1-ones were reacted with suitable 2-bromoacetophenones to give 2-[3/ 4-(2-substituted phenyl-2-oxoethoxy) benzylidene]-6-substituted-2,3-dihydro-1H-inden-1-one derivatives. The structure elucidation of the synthesised compounds was performed by IR, 1H-NMR, mass spectroscopic data and elemental analyses. The anticancer screening was carried out in National Cancer Institute (NCI), USA. Notable activity was obtained for some compounds.eninfo:eu-repo/semantics/closedAccess2,3-Dihydro-1H-Inden-1-OneAurone AnalogueAnticancer ActivityArticle11557858510.2174/1570180811666140403001212Q4Q3