İşcan, GökalpKürkçüoğlu, MineTosun, FatmaMiski, Mahmut2023-08-112023-08-112023İşcan, G., Kürkçüoğlu, M., Tosun, F. ve Miski, M. (2023). Biological activity and chemical composition of the essential oil from the fruits of Ferula rigidula Fisch. ex DC. Acta Pharmaceutica Sciencia, 61(3), 257-268. https://dx.doi.org/10.23893/1307-2080.APS61171307-2080https://dx.doi.org/10.23893/1307-2080.APS6117https://hdl.handle.net/20.500.12511/11312The hydro-distilled essential oils of the fruits of F. rigidula Fisch. ex DC. was analyzed by Gas Chromatography (GC) and Gas Chromatography/Mass Spectrometry (GC/MS) systems at the same time. Thirty-one compounds were characterized rep-resenting 98.2% of the essential oils. The main components of the oil were determined as a-pinene and camphene (24% and 20%, respectively). The anticandidal and antibacterial effects of the essential oil were determined by using partly modi-fied CLSI protocols M27-A2 and M7-A7, respectively. The essential oil of the dried fruits showed several inhibitory effects on the tested bacteria panel (MIC, 62.5 to 2000 µg/mL) and Candida species (MIC, 125 to 1000 µg/mL).eninfo:eu-repo/semantics/openAccessAntibacterialAnticandidalFerula RigidulaEssential OilGCMSArticle61325726810.23893/1307-2080.APS61172-s2.0-85166001094Q3