Tosu, Aydın RodiÇınar, TufanKalyoncuo?lu, MuhsinBiter, Halil İbrahimÇakal, SinemÇakal, BeytullahSelçuk, MuratBelen, ErdalCan, Mehmet Mustafa2023-03-142023-03-142022Tosu, A. R., Çınar, T., Kalyoncuo?lu, M., Biter, H. İ., Çakal, S., Çakal, B. ... Can, M. M. (2022). Predictive value of C-reactive protein/albumin ratio for no-reflow in patients with Non-ST-elevation myocardial infarction. Journal of Cardiovascular and Thoracic Research, 14(4), 214-219. https://dx.doi.org/10.34172/jcvtr.2022.305492008-51172008-6830https://dx.doi.org/10.34172/jcvtr.2022.30549https://hdl.handle.net/20.500.12511/10615Introduction: The focus of this research was to explore the link between CRP (C-reactive protein)/albumin ratio (CAR), a novel inflammatory response marker, and no-reflow (NR) phenomena in non-ST elevation myocardial infarction (non-STEMI) patients during percutaneous coronary intervention (PCI). Methods: The current study recruited 209 non-STEMI participants who underwent PCI. The patients were divided into two groups based on their post-intervention Thrombolysis in Myocardial Infarction (TIMI) flow grade; those with and without NR. Results: In all, 30 non-STEMI patients (6.9%) had NR after PCI. CAR values were substantially greater in the NR group. The CAR was identified to be a determinant of the NR (OR: 1.250, 95% CI: 1.033-1.513, P = 0.02), although CRP and albumin were not independently related with NR in the multivariate analysis. In our investigation, low density lipoprotein-cholesterol levels and high thrombus burden were also predictors of the occurrence of NR. According to receiver operating characteristic curve evaluation, the optimal value of CAR was > 1.4 with 60% sensitivity and 47% specificity in detecting NR in non-STEMI patients following PCI. Conclusion: To the best of knowledge, this is the first investigation to demonstrate that the CAR, a new and useful inflammatory marker, can be utilized as a predictor of NR in patients with non-STEMI prior to PCI.enAttribution 4.0 Internationalinfo:eu-repo/semantics/openAccessC-reactive ProteinCARNo-ReflowSerum AlbuminArticle14421421910.34172/jcvtr.2022.30549N/A0008903113000012-s2.0-8514902349336699552Q4