Determination of a new mutation in MT-ND1 gene of a patient with dextrocardia, ventriculoarterial discordance, and tricuspid atresia

Hatemi, Ali CanCeyran, HakanÜstek, Duran10.07.20192019-07-1010.07.20192019-07-102015Hatemi, A. C., Ceyran, H. ve Üstek, D. (2015). Determination of a new mutation in MT-ND1 gene of a patient with dextrocardia, ventriculoarterial discordance, and tricuspid atresia. Artificial Organs, 39(1), 83-84. https://dx.doi.org/10.1111/aor.124420160-564X1525-1594https://hdl.handle.net/20.500.12511/1388https://dx.doi.org/10.1111/aor.12442Tricuspid atresia, a congenital heart defect (CHD) with unknown etiology, occurs 0.056 per 100 live births and is invariably associated with right ventricular hypoplasia, and atrial/ventricular septal defects (1). Recently, many of associations have been reported between mitochondrial DNA (mtDNA) and a variety of diseases (2). Next-generation sequencing has overcome many limitations of mtDNA studies, such as estimation of heteroplasmy level and its effects on the severity of mitochondrial diseases.eninfo:eu-repo/semantics/embargoedAccessCongenital Heart DefectDNAmtDNADetermination of a new mutation in MT-ND1 gene of a patient with dextrocardia, ventriculoarterial discordance, and tricuspid atresiaLetter391838410.1111/aor.12442Q3Q2