Altaş, UğurÇevik, SedaKeser, BetülAlkaya, HalilKutlubay, BüşraAltaş, Zeynep MevaÖzkars, Mehmet Yaşar2025-11-262025-11-262025Altaş, U., Çevik, S., Keser, B., Alkaya, H., Kutlubay, B., Altaş, Z. M. ... Özkars, M. Y. (2025). Evaluation of the frequency of restless legs syndrome in children diagnosed with allergic diseases. Journal of Asthma, 62(1), 178-184. http://dx.doi.org/10.1080/02770903.2024.24381090277-09031532-4303http://dx.doi.org/10.1080/02770903.2024.2438109https://hdl.handle.net/20.500.12511/13248Objective: We aimed to determine the frequency of restless legs syndrome (RLS) in children with allergic diseases. Methods: The age, gender, height, weight, BMI z-scores, and laboratory values of children diagnosed with asthma, allergic rhinitis, atopic dermatitis, and chronic urticaria, as well as a healthy control group, were examined. RLS was assessed using a questionnaire based on the diagnostic criteria of the International Restless Legs Syndrome Study Group. Neurological examination findings, questionnaire results, and RLS severity scores were evaluated by a pediatric neurology specialist. Results: The study evaluated data from 270 children diagnosed with allergic diseases and 150 healthy controls. Both groups were statistically similar in terms of age, gender, weight, height, and BMI z-scores (p > 0.05). The frequency of RLS was reported as 13.3% in children with allergic airway disease, 15.5% in those with allergic skin disease, and 6.7% in the control group. The frequency of RLS in children with allergic airway disease and allergic skin disease was significantly higher compared to the control group (p = 0.041 and p = 0.022, respectively). The frequency of mild RLS in children with allergic diseases and the control group was 43.6% (n = 17) and 50% (n = 5), respectively (p = 0.737). The rate of females with RLS was significantly higher than those without RLS (69.2% vs. 30.8%) (p = 0.045). According to logistic regression analysis, individuals with allergic diseases were 2.307 (95.0% CI of OR 1.087 to 4.897) times more likely to develop RLS compared to those without allergic diseases (p = 0.029). Conclusion: The frequency of RLS is higher in children with allergic diseases. Early diagnosis of RLS may allow for a holistic management of quality-of-life-reducing problems, such as sleep disorders, that may be associated with both conditions.eninfo:eu-repo/semantics/openAccessAllergic RhinitisAsthmaAtopic DermatitisChildrenChronic UrticariaRestless Legs SyndromeArticle62117818410.1080/02770903.2024.2438109Q3WOS:0013744278000012-s2.0-8521133770839628098Q2