Üstün, NilüferGüven, Yeliz2022-11-212022-11-212022Üstün, N. ve Güven, Y. (2022). Effect of three different remineralizing agents on artificial erosive lesions of primary teeth. Australian Dental Journal, 67(3), 271-280. https://doi.org/10.1111/adj.129220045-04211834-7819https://doi.org/10.1111/adj.12922https://hdl.handle.net/20.500.12511/9998Background This study aimed to investigate the efficacy of three remineralizing agents on dental erosion in primary teeth. Methods Forty primary molars were randomly divided into four groups (n = 10 each): self-assembling peptide (P11-4), casein phosphopeptide-amorphous calcium fluoride phosphate (CPP-ACFP), sodium fluoride (NaF) and artificial saliva (AS; control). The erosion-like formation was created by immersing the samples in citric acid (4 x 2 min, pH 2.3) and AS (4 x 2 h, pH 7). The eroded samples were then treated with remineralizing agents and subjected to further erosion consisting of 15 cycles (3x/8-h interval) of immersion in citric acid and AS for 6 s each. Alterations in the mineral content and morphology of the samples were quantified using a microhardness tester and atomic force microscope. Results All agents had a significant remineralization effect on eroded primary tooth enamel. After further erosive challenge, enamel loss in the CPP-ACFP group was found to be significantly lower than in all other groups, and no significant difference was found between the P11-4 and NaF groups. Conclusions This study showed that all tested materials had remineralization ability, and CPP-ACFP had a superior effect in inhibiting enamel loss due to dental erosion in primary teeth.eninfo:eu-repo/semantics/embargoedAccessErosive LesionIn VitroPrimary TeethSelf-Assembling PeptideTooth RemineralizationArticle67327128010.1111/adj.12922Q30008157911000012-s2.0-8513272963635694835Q2