Doğan, CemBayram, ZübeydeCandan, ÖzkanOmaygenç, Mehmet OnurYılmaz, FatihAcar, Rezzan DenizAkbal, Özgür YaşarKaymaz, CihangirÖzdemir, Nihal10.07.20192019-07-1010.07.20192019-07-102017Doğan, C., Bayram, Z., Candan, Ö., Omaygenç, M. O., Yılmaz, F., Acar, R. D. ... Özdemir, N. (2017). Prediction of infarct size using two-dimensional speckle tracking echocardiography in acute myocardial infarction. Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques, 34(3), 376-382. https://dx.doi.org/10.1111/echo.134570742-28221540-8175https://dx.doi.org/10.1111/echo.13457https://hdl.handle.net/20.500.12511/2306WOS: 000398109300008PubMed ID: 28247458Background: This study aimed to determine the myocardial damage (infarct size provided by cardiac single-photon emission tomography) in early stages of the infarction using longitudinal strain and rotational parameters of the left ventricle. Methods: The study included 66 patients with anterior myocardial infarction (AMI) and 62 patients with inferior myocardial infarction (IMI) who underwent primary percutaneous intervention as well as a control group consisting of 50 healthy subjects. LV rotational parameters based on parasternal short-axis views in basal and apical planes and global longitudinal strain were measured with apical four-chamber, apical two-chamber, and apical long-axis views. Results: There was a significant positive correlation between infarct size and GLPSavg (r=-.55 <.001), GTOR angle (r=-.52, P<.001), apical rotation angle (r=-.40 <.001, and EF (r=-.43, <.001). While cutoff values were GLPSavg: 11.9 (AUC=0.78), GTOR angle: 11.4 degrees(AUC=0.77), apical rotation angle: 7.1 degrees (AUC=0.76) for patients with an infarct size greater than 20%, the cutoff values were GLPSavg: 10.7 (AUC=0.75), GTOR angle: 8.7 degrees (AUC=0.86), apical rotation angle: 4.35 degrees (AUC-0.87) for those with an infarct size greater than 40%. Conclusion: GLPSavg, GTOR angle, and apical rotation angle values may be used to determine the extent of infarction in early post-MI period, thereby allowing precautions to be taken for remodeling in early stages.eninfo:eu-repo/semantics/embargoedAccessMyocardial InfarctionMyocardial PerfusionRadionuclide ImagingStrainArticle34337638210.1111/echo.13457Q4N/A