Kaplan, ElmasEkizler, Firdevs A.Sarıbaş, HalenurTak, Bahar T.Çay, SerkanKorkmaz, AhmetÖzeke, ÖzcanÖzcan, FıratTopaloğlu, SerkanAras, Dursun2023-05-022023-05-022023Kaplan, E., Ekizler, F. A., Sarıbaş, H., Tak, B. T., Çay, S., Korkmaz, A. ... Aras, D. (2023). Effectiveness of the systemic immune inflammation index to predict atrial fibrillation recurrence after cryoablation. Biomarkers in Medicine, 17(2), 101-109. https://dx.doi.org/10.2217/bmm-2022-05151752-03711752-0363https://dx.doi.org/10.2217/bmm-2022-0515https://hdl.handle.net/20.500.12511/10909Background: We aimed to investigate the predictive role of systemic immune inflammation index (SII) on atrial fibrillation (AF) recurrence following cryoballoon-based AF ablation. Materials & methods: A total of 370 consecutive patients with symptomatic AF who underwent cryoablation were enrolled. The patients were divided into two groups according to recurrence development. Results: During the follow-up period of 25.0 ± 6.7 months, recurrence was observed in 77 patients (20.8%). Receiver operating characteristic analysis demonstrated that using a cutoff level of 532, SII had a sensitivity of 71% and specificity of 68%. In the multivariate Cox model, high SII was a significant predictor of the recurrence. Conclusion: This study showed that higher SII level is an independent predictor of AF recurrence.eninfo:eu-repo/semantics/closedAccessAtrial FibrillationBiomarkerCryoballoon AblationInflammationRecurrenceSystemic Immune Inflammation IndexArticle17210110910.2217/bmm-2022-0515Q40009730862000012-s2.0-8515262180237042445Q3