Eserdağ, SüleymanAkdağ Özkök, BurcuSüphan Erşahin, SuatYılmaz, Emine Zeynep2022-12-022022-12-022023Eserdağ, S., Akdağ Özkök, B., Süphan Erşahin, S. ve Yılmaz, E. Z. (2023). Vestibular hyaluronic acid injection in provoked vestibulodynia patients and its effect on pain and sexual function: A preliminary report. European Journal of Obstetrics and Gynecology and Reproductive Biology, 280, 64-67. https://doi.org/10.1016/j.ejogrb.2022.10.0270301-21151872-7654https://doi.org/10.1016/j.ejogrb.2022.10.027https://hdl.handle.net/20.500.12511/10061Objective: Provoked vestibulodynia (PVD) is a challenging and distressing problem for women. The aim of this study was to examine the effect of hyaluronic acid (HA) in the management of this condition. Method: This is a retrospective review of 12 women diagnosed with PVD and treated with HA (19 mg/mL) applied, point-by-point, to the vestibular region at 2 mm intervals and at a depth of 0.5 mm. Women completed a pain VAS and a Female Sexual Function Index (FSFI) before and 45 days after treatment. Results: An improvement was observed both in mean FSFI scores (17.8 to 23.3; p = 0.003) and mean VAS scores (7.2 to 4.1; p = 0.002) after HA application respectively. However, on a telephone interview 3 months post treatment, five women (41.7 %) complained of recurrence of their dyspareunia. Conclusion: HA is a promising management option in provoked vestibulodynia. However, further larger studies with possible alternative regimens and longer follow-up are required.eninfo:eu-repo/semantics/embargoedAccessFemale Sexual Function IndexHyaluronic AcidProvoked VestibulodyniaVisual Analogue ScaleArticle280646710.1016/j.ejogrb.2022.10.027Q30009131999000112-s2.0-8514244707336410243N/A