Kürkçüoğlu, Mineİşcan, GökalpTosun, FatmaMiski, Mahmut2023-03-222023-03-222023Kürkçüoğlu, M., İşcan, G., Tosun, F. ve Miski, M. (2023). Biological activity and chemical composition of the essential oil from the fruits of Ferula halophila Peşmen. Acta Pharmaceutica Sciencia, 61(1), 81-90. https://dx.doi.org/10.23893/1307-2080.APS61061307-2080https://dx.doi.org/10.23893/1307-2080.APS6106https://hdl.handle.net/20.500.12511/10660The hydrodistilled essential oils of the dried fruits of F. halophila Peşmen, an endemic species growing near Salt Lake in Central Anatolia, were analyzed by GC and GC-MS systems; 27 and 24 compounds representing 92.1% and 79.8% of the essential oils were characterized, respectively. The main component of the essential oils was identified as ?-phellandrene. The antibacterial and anticandidal effects of the essential oils were determined by using partly modified CLSI methods M7-A7 and M27-A2, respectively. The essential oils from two specimens showed weak to moderate inhibitory effects on the tested pathogenic bacteria (MIC, 125-2000 µg/ mL) and Candida panels (MIC, 156-1250 µg/mL).eninfo:eu-repo/semantics/closedAccessAntibacterialAnticandidalEssential OilFerula HalophilaArticle611819010.23893/1307-2080.APS61062-s2.0-85149247567Q3