Bölüm "İstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmasötik Toksikoloji Ana Bilim Dalı" WoS İndeksli Yayınlar Koleksiyonu için listeleme
Toplam kayıt 23, listelenen: 1-20
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Antioksidan maddelerin mutajenite üzerine etkilerinin ames testi ile incelenmesi
(Marmara Üniversitesi, 2017)Nowadays, several test systems have been developed in order to observe the mutagenic effects of chemical agents which play crucial roles in human health. The Ames Test is one of these test systems. With the Ames Test, some ... -
The association of oxidative stress and DNA damage with XRCC1 and XRCC3 polymorphisms in radiology technicians
(SAGE Publications Ltd, 2022)Ionizing radiation has widespread use in medicine in the diagnosis and treatment of many medical conditions. Radiology technicians are one group that is occupationally exposed to low doses of radiation. There are questions ... -
Biocompatibility of biomimetic multilayered alginate-chitosan/beta-TCP scaffold for osteochondral tissue
(Elsevier Science, 2015)Biomimetic three-layered monolithic scaffold (TLS) intended for treatment of osteochondral defects was fabricated by using freeze drying method. The multilayered material was prepared with chitosan (C) and alginate (A) ... -
Biological activities of the Ornithogalum orthophyllum and its in silico ADMET profile
(TMR Publishing Group, 2021)Background: The bulbs and aerial parts of Ornithogalum are used in Turkey both as food and to treat various ailments, and some of its medical applications are well known. However, the biological activities of Ornithogalum ... -
Chemical composition and in vitro mutagenic, antioxidant and anti-inflammatory activities of Lavandula angustifolia Mill. essential oil from Turkey
(Marmara University, 2022)The essential oil obtained from Lavandula angustifolia Mill. (Lavander) has many pharmacological effects, including antioxidant, antifungal, antibacterial and carminative effects. Lavandula angustifolia essential oil (LEO) ... -
Comparison of In vitro Anti-inflammatory, COX-1/COX-2 and LOX inhibitory activities of Malva sylvestris L. leaves and flowers extract
(Georg Thieme Verlag KG, 2023)... -
Comparison of inhaled and intraperitoneal formaldehyde toxicity in rats and the evaluation of the effects of melatonin
(Elsevier Ireland Ltd, 2016)Formaldehyde (FA) is a genotoxic substance that causes deleterious effects on the nervous system, respiratory system, and reproductive system as a result of occupational exposure. FA is also classified as human carcinogen ... -
Determination of aflatoxins and ochratoxin a levels in nuts and dried fruits in Turkey with evaluation of the estimated daily intake
(VUP Food Research Institute, 2023)A total of 140 samples, including nuts and dried fruits sold in the province of Istanbul, Turkey, were examined for the presence of aflatoxins and ochratoxin A (OTA) by high-performance liquid chromatography (HPLC), which ... -
The effect of carnitine against acrylamide-induced toxicity in rat lung and liver tissues
(Elsevier Ireland Ltd, 2016)Acrylamide (ACR) has the potential for cytotoxic and genotoxic effects by decreasing oxidative defense system and is known to be neurotoxic, hepatotoxic and carcinogenic to humans. Carnitine plays an important role in the ... -
The effect of granulocyte colony stimulating factor on genotoxicity in allogeneic peripheral blood stem cell transplantation donors: A prospective case-control study
(Turkish National Pediatric Society, 2023)Background. Every year, thousands of donors are exposed to granulocyte-colony stimulating factor (G-CSF) for stem cell mobilization in hematopoietic stem cell transplantations (HSCT). Previous studies about the genotoxicity ... -
Evaluation of clinical pharmacist interventions on drug-related problems in the gastroenterology ward
(Marmara University, 2022)Integrating clinical pharmacists in a multidisciplinary patient care team improves the treatment process by identifying and resolving drug-related problems (DRPs). The aim of the study was to determine the effect of clinical ... -
Evaluation of correlations between nutrients, fatty acids, heavy metals, and deoxynivalenol in corn (Zea mays L.)
(Oxford University Press, 2019)This study was conducted to develop linear regression equations to estimate nutrients, fatty acids, heavy metals, color characteristics (L,* a,* b*), and deoxynivalenol (DON) level of corn grains (n = 54) collected from ... -
Human biomonitoring of trace elements (Zn, Cu, Mn, Cd and As) level in a healthy urban population in Türkiye
(Marmara University, 2023)Human biomonitoring (HBM) studies are carried out to examine the effects of environmental pollutants on human health and to identify risks to public health, with the increasing awareness of environmental pollution around ... -
The influence of different extraction methods/solvents on composition, biological activities and ADMET predictions of phenolics in tribulus terrestris
(Instituto de Tecnologia do Parana, 2021)Tribulus terrestris is a plant that has medical importance in treating diseases such as cancer, urinary tract infections, kidney stones, rheumatism, and hypertension. The aim of this study is to examine the effects of ... -
Investigation of antioxidant and anticonvulsant activity of Hypericum triquetrifolium Turra
(Marmara University, 2022)Epilepsy is a state characterized by sudden, recurrent epileptic seizures that are not initiated by an identifiable event. There are various studies has been shown that Hypericum species may be used for their anticonvulsant ... -
Investigation of genotoxicity risk and DNA repair capacity in breast cancer patients using anastrozole
(Kare Publishing, 2018)OBJECTIVE: Breast cancer is the most common cancer in women worldwide and the incidence increases in postmenopausal women. Anastrozole is a non-steroidal (type II), third-generation aromatase inhibitor (AI) that is used ... -
Melatonin ameliorates oxidative DNA damage and protects against formaldehyde-induced oxidative stress in rats
(E-Century Publishing Corp, 2017)Formaldehyde (FA) is an organic chemical which is widely used all over the world and has hazardous effects for the environment. FA can react with many biomolecules in the biological systems and lead to toxic effects on ... -
Occurrence of fumonisins B1 and B2 in homemade medicinal plants: Exposure assessment in Northern Turkey
(Akademiai Kiado Rt., 2016)This study was conducted to determine the recent level of contamination with Fumonisin B1 (FB1) and Fumonisin B2 (FB2) in major medicinal plants and to assess consumer exposure in northern Turkey. FB1 and FB2 were investigated ... -
A pilot study on effects of combination usage of curcumin and melatonin on cisplatin treatment
(Elsevier Ireland Ltd, 2016)Cisplatin is an antitumor drug widely used in the treatmentof many malignant tumors. And also some studies show thatmelatonin and curcumin have antitumor activity via several mech-anisms including theirs in addition to ... -
Protective effect of N-Acetyl-L-Cysteine (NAC) on endosulfan-induced liver and kidney toxicity in rats
(E-Century Publishing Corp, 2017)Endosulfan-induced systemic toxicity arises from oxidative stress and glutathione depletion. This study aims to investigate the possible protective effect of N-acetyl-L-cysteine (NAC) against endosulfan-induced toxicity ...