Başlık için Sağlık Hizmetleri Meslek Yüksekokulu listeleme
Toplam kayıt 77, listelenen: 42-61
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Majistral ilaçlar: Olgu sunumu
(Adli Tıp Kurumu, 2016)Majistral ilaç, hasta için özel olarak hekim tarafından reçete edilen ve eczanede bu formüle göre hazırlanan ilaç olaraktanımlanmakta; majistral ilaçlarla ilgili hususlar Eczacılar ve Eczaneler Hakkında Yönetmelik hükümlerine ... -
Mechanistic insight into impact of phosphorylation on the enzymatic steps of farnesyltransferase
(Wiley, 2022)Farnesyltransferase (FTase) is a heterodimeric enzyme, which catalyzes covalent attachment of the farnesyl group to target proteins, thus coordinating their trafficking in the cell. FTase has been demonstrated to be highly ... -
Modeling and simulation of the "IL-36 cytokine" and CAR-T cells interplay in cancer onset
(World Scientific, 2022)Background: CAR-T cells are chimeric antigen receptor (CAR)-T cells; they are target-specific engineered cells on tumor cells and produce T cell-mediated antitumor responses. CAR-T cell therapy is the "first-line" therapy ... -
The multifactorial role of pre-supplementary motor area stimulation in the freezing of gait: An alternative strategy to the classical drug-Target approach
(Bentham Science Publishers, 2022)Introduction: The pre-supplementary motor area (Pre-SMA) plays a pivotal role in the control of voluntary motor control and freezing of gait (FOG) pathophysiological mechanism. Here, we aimed to modulate if the pre-SMA ... -
Na2Si3O7/BaO composites for the gamma-ray shielding in medical applications: Experimental, MCNP5, and WinXCom studies
(Pergamon-Elsevier Science Ltd, 2019)The role of BaO in the glassy structured Na2Si3O7 was investigated in the context of gamma radiations shielding parameters in the study. The mass attenuation coefficient, half layer value, and mean free path of the ... -
Neurons from human mesenchymal stem cells display both spontaneous and stimuli responsive activity
(Public Library of Science, 2020)Mesenchymal stem cells have the ability to transdifferentiate into neurons and therefore one of the potential adult stem cell source for neuronal tissue regeneration applications and understanding neurodevelopmental ... -
A novel comprehensive utilization of vanadium slag/epoxy resin/antimony trioxide ternary composite as gamma ray shielding material by MCNP 6.2 and BXCOM
(Elsevier, 2019)New research on composite materials was proposed for both gamma ray shielding and fireproofing. When compared to concrete, composite materials show up higher shielding properties in the 0.015 MeV–15 MeV incident energy ... -
Novel synthetic approaches for bisnaphthalimidopropyl (BNIP) derivatives as potential anti-parasitic agents for the treatment of leishmaniasis
(MDPI, 2019)Leishmaniasis is a neglected parasitic disease that is widely seen in more than 60 countries worldwide, including Turkey and its subcontinental region. There are several chemotherapy agents for the treatment of leishmaniasis, ... -
Novel β‑hydroxy ketones: Synthesis, spectroscopic characterization, molecular docking, and anticancer activity studies
(Elsevier B. V., 2022)In this study, a series of novel β‑hydroxy ketone derivatives 3a-o were designed, synthesized, and evaluated for their anticancer activity. The structure of these compounds were characterized by IR, 1H and 13C NMR, mass ... -
The optimal method to measure polyamines in serum by using HPLC fluorescence detector
(Istanbul Medipol University, 2023)Measurement of polyamines (putrescine, spermidine and spermine) is important in the monitoring of many metabolic events, as well as in cancer prognosis. However, the lack of method standardization and validation for the ... -
Optimization of inulin extraction from chicory roots and an ultrafiltration application to obtain purified inulin and hydrolyzed fructooligosaccharides
(Ankara University, 2024)Inulin and fructooligosaccharides (FOS) are prominent functional components in the food industry due to prebiotic and other pharmaceutical properties. Inulin is a storage polysaccharide in various plants. FOS are naturally ... -
Optimization of isothermal amplification method for Mycobacterium tuberculosis detection and visualization method for fieldwork
(Türkiye Klinikleri, 2020)Background/aim: Tuberculosis is still one of the most contagious diseases around the world. Key factors of tuberculosis control are rapid diagnostic, efficient treatment, and prevention of contamination by surveillance and ... -
Optimization of lyophilized LAMP and RT-PCR reaction mixes for detection of tuberculosis
(Sciendo, 2020)Undoubtedly, one of the most infectious diseases in the world is tuberculosis. Key factor for tuberculosis control is to prevent possible contagion with rapid diagnosis and effective treatment. The culture method, which ... -
Poor reactivity of posterior electroencephalographic alpha rhythms during the eyes open condition in patients with dementia due to Parkinson's disease
(Elsevier Inc., 2024)Here, we hypothesized that the reactivity of posterior resting-state electroencephalographic (rsEEG) alpha rhythms during the transition from eyes-closed to -open condition might be lower in patients with Parkinson's disease ... -
Potential of novel methyl jasmonate analogs as anticancer agents to metabolically target HK-2 activity in glioblastoma cells
(Frontiers Media S.A., 2022)Change in the energy metabolism of cancer cells, which display significant differences compared to normal cells, is a rising phenomenon in developing new therapeutic approaches against cancers. One of the metabolic enzymes, ... -
Preliminary findings on the role of high-frequency (5Hz) rTMS stimulation on M1 and pre-SMA regions in Parkinson's disease
(Elsevier Ireland Ltd, 2020)It has been already shown that the motor symptoms of the Parkinson's Disease (PD) have been improved with high frequency rTMS although there is no consensus on the most suitable target brain localization for a maximal ... -
Protective effect of edaravone on rat testis after valproic acid treatment
(Marmara University, 2022)Valproic acid n-dipropyl-acetic acid, VPA) is a medication used as anticonvulsant in the treatment of bipolar disorder, and for migraine prophylaxis. Long-term use of VPA is known to trigger reproductive impairment, which ... -
Radiation interaction parameters for blood samples of breast cancer patients: an MCNP study
(Springer, 2019)The main goal of this study was to determine radiation interaction parameters such as mass attenuation coefficients, effective atomic numbers, and effective electron densities depending on element concentrations (Na, K, ... -
Rapid molecular diagnosis of group a streptococcus with a novel loop mediated isothermal amplification method
(Verlag Klinisches Labor GmbH, 2022)Background: Group A Streptococcus (GAS) is the most common bacterial cause of acute tonsillopharyngitis. In this study, it was aimed to evaluate the performance of a novel Loop Mediated Isothermal Amplification (LAMP) ...