Ara
Toplam kayıt 28, listelenen: 21-28
Synthesis and in vitro antitumor activities of novel thioamide substituted piperazinyl-1,2,4-triazines
(Wiley, 2022)
Triazines are in great interest for their potential to mimic nucleoside analog compounds. Three different isomers exist including 1,2,3-triazine, 1,3,5-triazine (s-triazine) and 1,2,4-triazine. All of these skeletons were ...
Synthesis, antimicrobial activity and modeling studies of thiazoles bearing pyridyl and triazolyl scaffolds
(Walter de Gruyter GmbH, 2022)
In this study, novel 4-(5-((2/3/4-substituted benzyl)thio)-4-(4-substituted phenyl)-4H-1,2,4-triazol-3-yl)-2-(pyridin-3/4-yl)thiazoles were synthesized following a multi-step synthetic procedure. All the compounds were ...
Synthesis, characterization, COX1/2 inhibition and molecular modeling studies on novel 2-thio-diarylimidazoles
(Scientific Technical Research Council Turkey-Tubitak, 2021)
Heterocyclic compounds with diaryl substituents have been a milestone approach for selective cyclooxygenase 2 (COX 2) inhibition by bioisosteric replacements and modifications. It is also known that thiazole derivatives ...
Surgical orthopedic patients’ perception of antibiotic use and antibiotic resistance
(University of Ankara, 2023)
Objective: The aim of the study was to evaluate orthopedic patients' knowledge of antibiotics and antibiotic resistance. Material and Method: Patients admitted to the hospital for orthopedic surgery were given a questionnaire ...
A prospective study concerning the effect of pharmaceutical care services on patients with heart failure
(Marmara University, 2022)
Objective: Heart failure (HF), caused by an abnormality in cardiac function, is the inability of heart tissue to pump blood or deliver sufficient oxygen, resulting in abnormal diastolic volume. Drug-Related Problems (DRPs) ...
Synthesis and antibacterial evaluation of novel benzimidazole, benzothiazole, benzofurane, and naphtofurane derivatives of aminothiazoles
(Ankara Association of Pharmaceutical Sciences, 2022)
The thiazole ring is the core of bioactive molecules that generate broad activity. These activities include anticonvulsant, antimicrobial, antituberculosis, antiviral, etc. In this work, starting from seconder/cyclic amines, ...
Investigation of hidden crisis of prescription drug abuse in Turkey: Pregabalin monitoring
(Istanbul Medipol University, 2022)
This is a cross-sectional retrospective observational national study. Abuse/misuse of the pregabalin and related parameters analyzed. Pregabalin was mostly pre-scribed by general practitioners (26.2%). Pregabalin prescribing ...
The effect of decolonization-decontamination prophylaxis versus traditional prophylaxis in orthopedic surgery in Kosovo
(Istanbul Medipol University, 2024)
This study aimed to compare empirical prophylactic treatment with decoloni-zation-decontamination prophylaxis protocol in order to reduce surgical site infections. The study was conducted in Kosovo Ortomedica Orthopedic ...