WoS Q Kategorisi "Q2" Makale Koleksiyonu İçin Listeleme
Toplam kayıt 45, listelenen: 1-20
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3-Propionyl-thiazolidine-4-carboxylic acid ethyl esters: A family of antiproliferative thiazolidines
(Royal Society of Chemistry, 2015)Cancer results from unregulated cell growth. Reactivating the process of the programmed cell death, i.e. apoptosis, is a classical anticancer therapeutic strategy. The apoptosis-inducing property of the (2RS,4R)-2-phenyl ... -
ACE2 and LOX enzyme inhibitions of different lavender essential oils and major components linalool and camphor
(American Chemical Society, 2022)In this present study, Lavandula angustifolia, Lavandula stoechas, and Lavandula x heterophylla essential oils and their main compounds linalool and camphor were evaluated in vitro for lipoxygenase enzyme (LOX) and for ... -
An alternative approach to wound healing field; New composite films from natural polymers for Mupirocin dermal delivery
(Elsevier, 2019)In this study, novel adhesive films were prepared for Mupirocin dermal delivery. Natural polymers as chitosan, sodium alginate and carbopol were used for films development to evaluate possible interactions and drug release ... -
Anatolicin, a highly potent and selective cytotoxic sesquiterpene coumarin from the root extract of heptaptera anatolica
(MDPI, 2019)Seven known sesquiterpene coumarins and a new sesquiterpene coumarin, anatolicin (8), were isolated from the dichloromethane extract of the roots of Heptaptera anatolica. Structures of these compounds were elucidated based ... -
The anatomical, morphological features, and biological activity of Scilla siberica subsp. armena (Grossh.) Mordak (Asparagaceae)
(Springer Wien, 2023)Scilla siberica subsp. armena is known as Siberian Squill which is naturally distributed in Lebanon-Syria, Transcaucasus, and Turkey. It is a perennial bulbous plant with a short vegetation period from March to May. In ... -
Azelaic acid loaded chitosan and HPMC based hydrogels for treatment of acne: Formulation, characterization, in vitro-ex vivo evaluation
(Taylor & Francis Ltd, 2022)In this study, hydrogels containing azelaic acid were developed using chitosan or HPMC (1-7%) for local treatment of acne vulgaris. Physicochemical properties such as viscosity, pH and mechanical properties were evaluated. ... -
Binary synergistic combinations of lavender and fennel essential oils with amoxicillin
(Georg Thieme Verlag, 2023)Microbial resistance is an important problem in modern healthcare systems. In addition to drug resistance, the side effects of current antibiotic applications are also known issues. In this present study, binary combinations ... -
Combination therapy with chitosan/siRNA nanoplexes targeting PDGF-D and PDGFR-beta reveals anticancer effect in breast cancer
(Wiley, 2023)Background: Platelet derived growth factors (PDGF)-D and the expression of its receptor increase in neoplastic progression of cancer. Co-silencing of growth factor and receptor can be suggested as an important strategy for ... -
Cytotoxic activity and docking studies of 2-arenoxybenzaldehyde N-acyl hydrazone and 1,3,4-oxadiazole derivatives against various cancer cell lines
(MDPI, 2022)To understand whether previously synthesized novel hydrazone and oxadiazole derivatives have promising anticancer effects, docking studies and in vitro toxicity assays were performed on A-549, MDA-MB-231, and PC-3 cell ... -
Development, characterization of naringenin-loaded promising microemulsion formulations, and demonstration of anti-aging efficacy by in vitro enzyme activity and gene expression
(Editions de Sante, 2023)This study aims to produce microemulsion formulations containing naringenin for anti-aging reasons. For this purpose, formulations of topical microemulsions including different cosurfactants and surfactants were developed, ... -
Energy drink induced lipid peroxidation and oxidative damage in rat liver and brain when used alone or combined with alcohol
(Wiley, 2017)Energy drinks (ED) are containing large doses of metabolic stimulants and its use with ethanol has increased dramatically among young adults. In this study, we examined the effects of ED exposure either alone or in combination ... -
Enzyme-based antiviral potential of cinnamomum verum j. presl. essential oil and ıts major component (e)-cinnamaldehyde
(2024)In the present study, Cinnamomum verum J. Presl. bark essential oil and its main component cinnamaldehyde was evaluated in vitro for neuraminidase (NA), transmembrane serine protease (TMPRSS2), and angiotensin converting ... -
Formulation development of liposomal coffee extracts and investigation of their antioxidant capacities
(Elsevier, 2021)he main objective of this study was to carry out the antioxidant capacity of a liposomal formulation either green coffee extract (GCE) and medium roasted coffee extract (RCE) in aq. and MeOH. First, the coffee beans were ... -
Formulation development of Silybum marianum seed extracts and silymarin nanoparticles, and evaluation of hepatoprotective effect
(Editions de Sante, 2023)In this study, we formulated silymarin-nanoparticles and assayed their ability to reduce acetaminophen-induced toxicity in vitro and in vivo. After silymarin molecules were encapsulated the loading efficiency and the ... -
Glycopolymer decorated multiwalled carbon nanotubes for dual targeted breast cancer therapy
(Royal Society of Chemistry, 2020)Carbon-based nanomaterials (CNMs) have attracted great attention in biomedical applications such as cancer imaging and therapy. CNMs, which are currently used in a wide range of applications, suffer from drawbacks of ... -
HPLC-FRAP methodology and biological activities of different stem bark extracts of Cajanus cajan (L.) Millsp
(Elsevier, 2021)Cajanus cajan. (L.) Millsp. (C. cajan) (Family: Fabaceae) also known as pigeon pea, is a famous food and cover/forage crop bearing a high amount of key amino acids (methionine, lysine and tryptophan). This study investigated ... -
Improving therapeutic efficacy of voriconazole against fungal keratitis: Thermo-sensitive in situ gels as ophthalmic drug carriers
(Elsevier Science Bv, 2019)The aim of this research was to evaluate the potential use of in situ gel formulations for voriconazole ocular delivery as fungal keratitis treatment. The in situ gelling system was applied to increase residence time and ... -
In vitro activities of colistin, tigecycline and tobramycin, alone or in combination, against carbapenem-resistant enterobacteriaceae strains
(Elsevier, 2015)The aim of this study was to investigate the activities of various antibiotics, alone or in combination, against carbapenem-resistant Enterobacteriaceae (CRE). Minimum inhibitory concentrations (MICs) of meropenem, colistin, ... -
In vitro and in silico evaluation of ACE2 and LOX inhibitory activity of origanum essential oils and carvacrol
(Georg Thieme Verlag KG, 2023)Origanum spp. are used both for culinary purposes and for their biological activities. In this study, commercial Origanum majorana, Origanum minutiflorum, Origanum vulgare, and Origanum onites essential oils and their ... -
In vitro anti-inflammatory and anticancer evaluation of mentha spicata l. and matricaria chamomilla l. essential oils
(American Chemical Society, 2023)Spearmint, Mentha spicata L., and the German chamomile, Matricaria chamomilla L., preparations are used against inflammatory conditions traditionally and in modern medicinal applications. This present study aimed to evaluate ...