Can ablation win against partial nephrectomy and become first line therapy in cT1a renal tumours?
Künye
Sandbergen, L., Güven, S. ve del Pilar Laguna Pes, M. (2019). Can ablation win against partial nephrectomy and become first line therapy in cT1a renal tumours? Current Opinion in Urology, 29(1), 70-77. https://dx.doi.org/10.1097/MOU.0000000000000559Özet
Purpose of review Currently, small renal masses account for the largest proportion of renal tumour and small renal cell carcinomas (RCC). Although partial nephrectomy, whenever possible, is recognized as the gold standard for treatment, thermal ablation has gained increasing attention as optional treatment in a population sector harbouring small renal masses/small RCCs. The purpose of this review is to update comparative outcomes between these two options of treatment. Recent findings Recent observational case-control and population-based cohorts applying propensity score or inverse probability treatment weighted methodology adjusting for baseline patient and tumour characteristics, compare outcomes between partial nephrectomy and thermal ablation (both cryotherapy and radiofrequency), radical nephrectomy and thermal ablation and between thermal ablation and nonsurgical management. Most of them focus on T1aRCC. Summary Comparative outcomes' evidence is limited to population-based or institutional series adjusted for baseline differences and systematic reviews. With exception of special clinical situations, thermal ablation provides similar estimated 5-year cancer and overall survival with a clear benefit in postoperative outcomes when compared to partial nephrectomy in cT1a older patients. The trade-off is more evident when thermal ablation is compared to radical nephrectomy. The advantages in terms of adverse events persist up to 1 year after treatment. Benefits are less apparent in solitary kidneys and when synchronous bilateral approaches are performed.
WoS Q Kategorisi
Q3Scopus Q Kategorisi
Q1Kaynak
Current Opinion in UrologyCilt
29Sayı
1Koleksiyonlar
İlgili Öğeler
Başlık, yazar, küratör ve konuya göre gösterilen ilgili öğeler.
-
Utilization and operative influence of renal mass biopsy in the small renal mass: Analysis from the clinical research office of the endourological society small renal mass registry
Shahait, Mohammed; Jackman, Stephen; Landman, Jaime; Lechevallier, Eric; Billiet, Ignace; Fossion, Laurent; Aslan, Yılmaz; Laguna Pes, Maria Del Pilar (Mary Ann Liebert, 2020)Introduction and Objective: Definitive inclusion of renal mass biopsy (RMB) in small renal mass (SRM) diagnostic algorithm remains controversial. We assessed incidence and accuracy of RMB in SRMs in the CROES Renal Mass ... -
Correlation between cerebral-renal near-infrared spectroscopy and ipsilateral renal perfusion parameters as clinical outcome predictors after open heart surgery in neonates and infants
Örmeci̇, Tuǧrul; Alkan-Bozkaya, Tijen; Özyüksel, Arda; Ersoy, Cihangir; Ündar, Akif; Akçevin, Atıf; Türkoǧlu, Halil (Blackwell Publishing, 2015)The objective of this clinical study is to determine whether correlation exists among cerebral and renal near-infrared spectroscopy (NIRS) measurements, renal Doppler ultrasonography parameters (resistive index, peak ... -
Ex vivo resection and renal autotransplantation for the treatment of a large renal vein aneurysm causing recurrent pulmonary embolism and a coexisting vascular malformation: A case report
Özyüksel, Arda; Aktaş, Sema; Çalıs, Elif; Erol, Cengiz; Sevmiş, Şinasi (Sage Publications Inc, 2016)A 36-year-old young woman with a medical history of recurrent pulmonary embolism and chronic pelvic pain was admitted to our hospital. Contrast-enhanced imaging techniques revealed a large left renal vein aneurysm with a ...