dc.contributor.author | Durdu, Salih | |
dc.contributor.author | Cihan, Gizem | |
dc.contributor.author | Yalçın, Emine | |
dc.contributor.author | Çavuşoğlu, Kültigin | |
dc.contributor.author | Altınkök, Atılgan | |
dc.contributor.author | Sağcan, Hasan | |
dc.contributor.author | Yurtsever, İlknur | |
dc.contributor.author | Usta, Metin | |
dc.date.accessioned | 2023-07-28T11:35:16Z | |
dc.date.available | 2023-07-28T11:35:16Z | |
dc.date.issued | 2023 | en_US |
dc.identifier.citation | Durdu, S., Cihan, G., Yalçın, E., Çavuşoğlu, K., Altınkök, A., Sağcan, H. ... Usta, M. (2023). Surface characterization, electrochemical properties and in vitro biological properties of Zn-deposited TiO2 nanotube surfaces. Scientific Reports, 13(1). https://dx.doi.org/10.1038/s41598-023-38733-2 | en_US |
dc.identifier.issn | 2045-2322 | |
dc.identifier.uri | https://dx.doi.org/10.1038/s41598-023-38733-2 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/11275 | |
dc.description.abstract | In this work, to improve antibacterial, biocompatible and bioactive properties of commercial pure titanium (cp-Ti) for implant applications, the Zn-deposited nanotube surfaces were fabricated on cp-Ti by using combined anodic oxidation (AO) and physical vapor deposition (PVD-TE) methods. Homogenous elemental distributions were observed through all surfaces. Moreover, Zn-deposited surfaces exhibited hydrophobic character while bare Ti surfaces were hydrophilic. Due to the biodegradable behavior of Zn on the nanotube surface, Zn-deposited nanotube surfaces showed higher corrosion current density than bare cp-Ti surface in SBF conditions as expected. In vitro biological properties such as cell viability, ALP activity, protein adsorption, hemolytic activity and antibacterial activity for Gram-positive and Gram-negative bacteria of all surfaces were investigated in detail. Cell viability, ALP activity and antibacterial properties of Zn-deposited nanotube surfaces were significantly improved with respect to bare cp-Ti. Moreover, hemolytic activity and protein adsorption of Zn-deposited nanotube surfaces were decreased. According to these results; a bioactive, biocompatible and antibacterial Zn-deposited nanotube surfaces produced on cp-Ti by using combined AO and PVD techniques can have potential for orthopedic and dental implant applications. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Nature Research | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.rights | Attribution 4.0 International | * |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | TiO2 Nanotube Surfaces | en_US |
dc.subject | Vitro Biological Properties | en_US |
dc.subject | Electrochemical Properties | en_US |
dc.title | Surface characterization, electrochemical properties and in vitro biological properties of Zn-deposited TiO2 nanotube surfaces | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Scientific Reports | en_US |
dc.department | İstanbul Medipol Üniversitesi, Sağlık Hizmetleri Meslek Yüksekokulu, Tıbbi Laboratuvar Teknikleri Ana Bilim Dalı | en_US |
dc.authorid | 0000-0002-4257-8543 | en_US |
dc.authorid | 0000-0001-7944-5077 | en_US |
dc.identifier.volume | 13 | en_US |
dc.identifier.issue | 1 | en_US |
dc.relation.tubitak | info:eu-repo/grantAgreement/TUBITAK/SOBAG/118M766 | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1038/s41598-023-38733-2 | en_US |
dc.institutionauthor | Sağcan, Hasan | |
dc.institutionauthor | Yurtsever, İlknur | |
dc.identifier.wosquality | Q2 | en_US |
dc.identifier.wos | 001030642400017 | en_US |
dc.identifier.scopus | 2-s2.0-85164755730 | en_US |
dc.identifier.pmid | 37452093 | en_US |
dc.identifier.scopusquality | Q1 | en_US |