Atherogenic index of plasma and triglyceride- glucose index to predict more advanced coronary artery diseases in patients with the first diagnosis of acute coronary syndrome
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info:eu-repo/semantics/embargoedAccessTarih
2023Yazar
Özen, YasinÖzbay, Mustafa Bilal
Yakut, İdris
Kanal, Yücel
Abdelmottelaeb, W.
Nriagu, Bede N.
Salmon, J. T. S.
Quintanilla, B.
Munguia, C.
Castro, T. Reyes
Sherpally, Deepak
Ertem, Ahmet Göktuğ
Yayla, Çağrı
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Özen, Y., Özbay, M. B., Yakut, İ., Kanal, Y., Abdelmottelaeb, W., Nriagu, B. N. ... Yayla, Ç. (2023). Atherogenic index of plasma and triglyceride- glucose index to predict more advanced coronary artery diseases in patients with the first diagnosis of acute coronary syndrome. European Review for Medical and Pharmacological Sciences, 27(9), 3993-4005. https://dx.doi.org/10.26355/eurrev_202305_32305Özet
OBJECTIVE: Coronary heart dis-ease (CHD) is the most common cause of mor-tality and morbidity. Acute coronary syndrome (ACS) is the most advanced form of the CHD spectrum. The triglyceride-glucose index (TGI) and atherogenic plasma index (AIP) are asso-ciated with future cardiovascular events. This study investigated the association of these pa-rameters with the severity of CAD and prognosis in the first-diagnosed ACS patients.PATIENTS AND METHODS: Our study was designed retrospectively, including 558 patients. Patients were divided into four subgroups: high and low TGI and high and low AIP. SYNTAX scores, in-hospital mortality, major adverse car-diac events (MACE), and survival were com-pared at 12-month follow-up.RESULTS: More three-vessel disease and high-er SYNTAX scores have been detected in the high AIP and TGI groups. More MACEs have been ob-served in high AIP and TGI groups than low groups. AIP and TGI were found to be independent predic-tors for SYNTAX = 23. While AIP has been found to be an independent risk factor for MACE, TGI has not been detected as an independent risk factor. In addition to AIP, age, three-vessel disease, and low-er EF were the independent risk factors for MACE. Survival was lower in high TGP and AIP groups.CONCLUSIONS: AIP and TGI are costless bedside parameters that can be easily calculat-ed. These parameters can predict the severity of CAD in first-diagnosed ACS patients. Besides, AIP is an independent risk factor for MACE. AIP and TGI parameters can guide our treatment in this patient population.
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European Review for Medical and Pharmacological SciencesCilt
27Sayı
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