Yazar "Parlar Köprülü, Rabia Edibe" için listeleme
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Alloksanla oluşturulmuş diyabetik sıçan modelinde vinkamin'in spermatogenez üzerindeki etkilerinin araştırılması
Parlar Köprülü, Rabia Edibe (İstanbul Medipol Üniversitesi, Sağlık Bilimleri Enstitüsü, 2022)Diabetes mellitus sıklıkla retinopati, nöropati ve nefropati dahil olmak üzere çeşitli organ sistemlerinin sorunlarıyla bağlantılıdır. Ek olarak, hastaların cinsel işlevlerinde libido ve doğurganlıkta azalma gibi değişiklikler ... -
Effect of glabridin on microvascular permeability of plasma proteins induced by carrageenan
Parlar Köprülü, Rabia Edibe; Parlar, Ali; Çam, Saliha Ayşenur; Arslan, Seyfullah Oktay (Biointerface Research in Applied Chemistry, 2022)In present study, investigate the anti-inflammatory effects of glabridin (GLA) in the carrageenan-induced paw edema test of rats. Inflammation is an answer to the body's immune response to various stimuli such as physical ... -
Effects of vincamine on testicular dysfunction in alloxan-induced diabetic male rats
Parlar Köprülü, Rabia Edibe; Okur, Mehmet Evren; Kolbaşı, Bircan; Keskin, İlknur; Özbek, Hanefi (Brieflands, 2022)Background: Diabetes mellitus (DM) is frequently linked with problems of several organ systems, including retinopathy, neuropathy, and nephropathy. Additionally, patients have changes in sexual functioning, such as decreased ... -
Extract of Glycyrrhiza glabra root attenuates nociception in experimental pain models: The role of BKCa channels
Parlar, Ali; Parlar Köprülü, Rabia Edibe; Arslan, Seyfullah Oktay; Çam, Saliha Ayşenur; Pesen Özdoğan, Fidan; Yumrutaş, Önder; Üçkardeş, Fatih; Rios, Miguel; Martinez, Jose L. (MS Editions, 2022)The aim of this study was to evaluate the functional interaction of Glycyrrhiza glabra root extract (GGRE) on the large conductance Ca2+-activated K+ (BKCa) channels expressed in the peripheral nervous system by using ... -
How to create an experimental diabetes mellitus model?
Parlar Köprülü, Rabia Edibe (Pensoft Publishers, 2023)Diabetes is a metabolic disorder characterized by chronic hyperglycemia. Early treatment is very important in terms of preventing diabetes-related late complications with high treatment costs and increasing the patient’s ... -
Phytochemical compounds loaded to nanocarriers as potential therapeutic substances for alzheimer’s disease-could they be effective?
Polat, Derya Çiçek; Karadağ, Ayşe Esra; Parlar Köprülü, Rabia Edibe; Karantas, Ioannis D.; Mutlu, Gökçe; Çağlar, Emre Şefik; Okur, Mehmet Evren; Üstündağ Okur, Neslihan; Siafaka, Panoraia I. (Bentham Science Publishers, 2022)Alzheimer's disease accounts for a high percentage of dementia cases in elderly individuals. This type of brain disease is caused by damage to the brain cells affecting the ability of the patients to communicate, as well ... -
Protein and gene delivery systems for neurodegenerative disorders: Where do we stand today?
Siafaka, Panoraia I.; Okur, Mehmet Evren; Dilsiz Erim, Pelin; Çağlar, Emre Şefik; Özgenç, Emre; Gündoğdu, Evren; Parlar Köprülü, Rabia Edibe; Karantaş, Ioannis D.; Üstündağ Okur, Neslihan (MDPI, 2022)It has been estimated that every year, millions of people are affected by neurodegenerative disorders, which complicate their lives and their caregivers’ lives. To date, there has not been an approved pharmacological ... -
Yara fizyolojisi ve deneysel yara modelleri: Geleneksel derleme
Parlar Köprülü, Rabia Edibe; Mutlu, Gökçe; İpekçi, Esra; Okur, Mehmet Evren (Türkiye Klinikleri Yayınevi, 2022)Yara, vücuda gelebilecek bir yaralanma sonucu cildin epidermisinde hasar oluşması ve derinin normal anatomisinin ve fonksiyonlarının bozulması olarak tanımlanır. Yara iyileşmesi, kazayla veya kasıtlı olarak meydana gelen ...