Yazar "Koçak, Mehmet" için listeleme
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Active shrinkage protects neurons following axonal transection
Aydın, Mehmet Şerif; Bay, Sadık; Yiğit, Esra Nur; Özgül, Cemil; Kaval Oğuz, Elif; Yenidünya Konuk, Elçin; Ayşit, Neşe; Cengiz, Nureddin; Erdoğan, Ender; Him, Aydın; Koçak, Mehmet; Eroğlu, Emrah; Öztürk, Gürkan (Elsevier Inc., 2023)Trauma, vascular events, or neurodegenerative processes can lead to axonal injury and eventual transection (axotomy). Neurons can survive axotomy, yet the underlying mechanisms are not fully understood. Excessive water ... -
Diyet magnezyum alımı ile uyku kalitesi ve yorgunluk arasındaki ilişki: Kesitsel çalışma
Adıgüzel, Aysel Ayça; Erdem, Nihal Zekiye; Koçak, Mehmet (Türkiye Klinikleri Yayınevi, 2023)Amaç: Magnezyumun uyku ve yorgunluk ile ilgili konularda et- kili olduğu düşünülmektedir. Bu çalışmada, erişkin bireylerde diyet magnezyum alımı ile uyku kalitesi ve yorgunluk arasındaki ilişkinin incelenmesi amaçlanmaktadır. ... -
An examination of health care utilization during the COVID-19 pandemic among women with early-stage hormone receptor-positive breast cancer
Paladino, Andrew J.; Pebley, Kinsey; Koçak, Mehmet; Krukowski, Rebecca A.; Waters, Teresa M.; Vidal, Gregory; Schwartzberg, Lee S.; Curry, Andrea N.; Graetz, Ilana (BioMed Central Ltd, 2022)Background: Women undergoing treatment for breast cancer require frequent clinic visits for maintenance of therapy. With COVID-19 causing health care disruptions, it is important to learn about how this population’s access ... -
Gender-specific modeling of growth profiles in pre-school-age children
Koçak, Mehmet; Wolde, Alemayehu; Tylavsky, Frances A. (Türkiye Klinikleri, 2020)Objective: In pediatric clinical trials and cohort stu ies, actual height, weight and head circumference of children at a specific age may be required for certain developmental assessments such as energy expenditure. This ... -
Individual ingredients of NP-101 (Thymoquinone formula) inhibit SARS-CoV-2 pseudovirus infection
Maen, Abdelrahim; Gök Yavuz, Betül; Mohamed, Yehia I.; Esmail, Abdullah; Lu, Jianming; Mohamed, Amr; Azmi, Asfar S.; Kaseb, Mohamed; Kasseb, Osama; Li, Dan; Gocio, Michelle; Koçak, Mehmet; Selim, Abdelhafez; Ma, Qing; Kaseb, Ahmed O. (Frontiers Media Sa, 2024)Thymoquinone TQ, an active ingredient of Nigella Sativa, has been shown to inhibit COVID-19 symptoms in clinical trials. Thymoquinone Formulation (TQF or NP-101) is developed as a novel enteric-coated medication derivative ... -
Migraine severity, disability, and duration: Is a good diet quality, high intake of phytochemicals and polyphenols important?
Bakırhan, Hande; Pehlivan, Merve; Uyar Cankay, Tuğba; Koçak, Mehmet (Frontiers Media S.A., 2022)Objectives: Dietary pattern may be the determinant of migraine prognosis through various mechanisms such as systemic inflammation, vasodilation, cerebral glucose metabolism, and mitochondrial dysfunction. This study was ... -
Modeling the end date of COVID-19 pandemic
Koçak, Mehmet (Türkiye Klinikleri, 2020)Objective:As we have been living through COVID-19 pandemic for more than 5 months with its all detrimental im-pacts on our economic, social, and individual lives, developing models that will accurately inform us about the ... -
A pooled RT-PCR testing strategy for more efficient Covid-19 pandemic management
Ayaz, Akif; Öztürk Demir, Aslı Güner; Öztürk, Gürkan; Koçak, Mehmet (Elsevier, 2022)Objectives: RT-PCR testing is indispensable in Covid-19 pandemic management. With the spread of the pandemic with emerging variants, the RT-PCR capacity is overburdened and new strategies and capabilities need to be ... -
A randomized, double-blind, placebo-controlled, multicenter study to evaluate the safety and efficacy of thymoquinone formula (TQF) for treating outpatient SARS-CoV-2
Bencheqroun, Hassan; Ahmed, Yasir; Koçak, Mehmet; Villa, Enrique; Barrera, Cesar; Mohiuddin, Mariya; Fortunet, Raul; Iyoha, Emmanuel; Bates, Deborah; Okpalor, Chinedu; Agbosasa, Ola; Mohammed, Karim; Pondell, Stephen; Mohamed, Amr; Mohamed, Yehia I.; Gök Yavuz, Betül; Kaseb, Mohamed O.; Kasseb, Osama O.; Gocio, Michelle York; Tu, Peter Tsu-Man; Li, Dan; Lu, Jianming; Selim, Abdulhafez; Ma, Qing; Kaseb, Ahmed O. (MDPI, 2022)There is an urgent need for an oral drug for the treatment of mild to moderate outpatient SARS-CoV-2. Our preclinical and clinical study's aim was to determine the safety and preliminary efficacy of oral TQ Formula (TQF), ... -
Spatial association of environmental and dietary factors with copd deaths
Aktaş, Selman; Tüzüner, Begüm; Mergen, Mahmut; Sultan-Ali, İbrahim; Koçak, Mehmet (Dove Medical Press Ltd, 2022)Introduction: Chronic obstructive pulmonary disease (COPD) remains a significant health concern globally and spatiotemporal investigations on the etiology and progression of COPD are needed to develop more effective and ... -
Stratification of the gut microbiota composition landscape across the alzheimer's disease continuum in a Turkish cohort
Yıldırım, Süleyman; Nalbantoğlu, Özkan Ufuk; Bayraktar, Abdulahad; Ercan, Fatma Betül; Gündoğdu, Aycan; Velioğlu, Halil Aziz; Göl, Mehmet Fatih; Ekinci Soylu, Ayten; Koç, Fatma; Aslan Gülpınar, Ezgi; Soğukkanlı Kadak, Kübra; Arıkan, Muzaffer; Mardinoğlu, Adil; Koçak, Mehmet; Köseoğlu, Emel; Hanoğlu, Lütfü (American Society for Microbiology, 2022)Alzheimer's disease (AD) is a heterogeneous disorder that spans a continuum with multiple phases, including preclinical, mild cognitive impairment, and dementia. Unlike for most other chronic diseases, human studies reporting ... -
Tocilizumab treatment in severe COVID-19: A multicenter retrospective study with matched controls
Mert, Ali; Vahaboğlu, Haluk; Arslan, Ferhat; Batirel, Ayşe; Saraçoğlu, Kemal Tolga; Baştuğ, Aliye; Çağatay, Atahan; Irmak, İlim; Telli Dizman, Gülçin; Ertenli, İhsan; Altunal, Lütfiye Nilsun; Ertürk Şengel, Buket; Bayram, Mehmet; Omma, Ahmet; Amikishiyev, Shirkhan; Aypak, Adalet; Bes, Cemal; Bölükçü, Sibel; İçten, Sacit; Topeli, Arzu; Bektaş, Murat; Arslan, Birsen Yiğit; Öztürk, Sinan; Çomoğlu, Şenol; Aydın, Selda; Küçükşahin, Orhan; İçaçan, Ozan Cemal; İnce, Burak; Aghamuradov, Sarvan; Yalçın Mutlu, Melek; Şimşek, Funda; Emre, Salih; Üstün, Cemal; Ergen, Pınar; Aydın, Özlem; Koç, Meliha Meriç; Sevindik, Ömür Gökmen; Odabaşı, Zekaver; Korten, Volkan; Bodur, Hürrem; Güner, Rahmet; Ünal, Serhat; Koçak, Mehmet; Gül, Ahmet (Springer Heidelberg, 2022)Coronavirus disease-2019 (COVID-19) associated pneumonia may progress into acute respiratory distress syndrome (ARDS). Some patients develop features of macrophage activation syndrome (MAS). Elevated levels of IL-6 were ... -
A two-stage diagnosis strategy for COVID-19 and similar pandemics
Koçak, Mehmet; Cece, Sinem; Türkay, Tuğçe (Türkiye Klinikleri, 2021)Objective: Coronavirus disease-2019 (COVID-19) outbreak emerged in Wuhan-China in December-2019, and has covered the world by rapidly becoming a pandemic, infecting >4.5 million by mid-May 2020, killing >300,000 globally, ... -
When bladder and brain collide: Is there a gender difference in the relationship between urinary incontinence, chronic depression, and anxiety?
Daşdelen, Muhammed Furkan; Almas, Furkan; Çelik, Süleyman; Çelik, Nursanem; Seyhan, Züleyha; del Pilar Laguna Pes, Maria; Albayrak, Selami; Horuz, Rahim; Koçak, Mehmet; de la Rosette, Jean J. M. C. H. (Multidisciplinary Digital Publishing Institute (MDPI), 2023)In longitudinal and cross-sectional studies, depression and anxiety have been associated with urinary incontinence (UI) in women. However, this association has not been studied in men. Utilizing data from the 2008 Turkish ...