Yazar "Şeker, Mesut" için listeleme
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Beyond traditional therapies: clinical significance of complex molecular profiling in patients with advanced solid tumours—results from a Turkish multi-centre study
Ölmez, Ömer Fatih; Bilici, Ahmet; Er, Özlem; Bişgin, Atıl; Sevinç, Alper; Akman, Tülay; Uslu, Rüçhan; Molinas Mandel, Nil; Yalçın, Şuayib; Teomete, Mehmet; Görümlü, Gürbüz; Demir, Atakan; Namal, Esat; Alıcı, Süleyman; Selçukbiricik, Fatih; Bavbek, Sevil; Paksoy, Fatma; Başaran, Gül; Özer, Leyla; Şener, Nur; Harputluoğlu, Hakan; Kaya, Ali Osman; Yazar, Aziz; Afşar, Çiğdem Usul; Göker, Erdem; Şen, Fatma; Gököz Doğu, Gamze; Şeker, Mesut; Özkan, Metin; Türken, Orhan; Özveren, Ahmet; Orhan, Bülent; Yumuk, Fulden; Üskent, Necdet; Saip, Pınar; Şanlı, Ulus Ali; Dişel, Umut; Berk, Veli; Alakavuklar, Mehmet (2024)Objective: The objective of this multi-centre, real-world study was to examine the potential influence of comprehensive molecular profiling on the development of treatment decisions or adjustments for patients with advanced ... -
The changing of serum vitamin B-12 and homocysteine levels after gastrectomy in patients with gastric cancer: do they associate with clinicopathological factors?
Bilici, Ahmet; Sonkaya, Alper; Ercan, Şerif; Ustaalioğlu, Bala Başak Öven; Şeker, Mesut; Aliustaoǧlu, Mehmet; Orçun, Asuman; Gümüş, Mahmut (Springer, 2015)After total (TG) or distal subtotal gastrectomy (DG), patients are at high risk of vitamin B-12 (vit-B-12) deficiency, which results in elevation of homocysteine levels. The changing of serum vit-B-12 and homocysteine ... -
The clinical and pathologic characteristics of 400 gastrointestinal stroinal tumor patients from Turkey: The final results of the Turkish Anatolian Society of Medical Oncology Multicenter Registery
Sevinç, Alper; Şeker, Mesut; Yıldız, Ramazan; Cihan, Şener; Kaplan, Mehmet Ali; Dane, Faysal; Karaca, Halit; Üyetürk, Ümmügül; Bilici, Ahmet; Özdemir, Nuriye; Uncu, Doğan; Salepçi, Tafian; Işıkdoğan, Abdurrahman; Benekli, Mustafa; Özkan, Metin; Gümüş, Mahmut; Öksüzoğlu, Berna (American Society of Clinical Oncology, 2014)… -
Clinical role of 18F-FDG-PET/CT in the assessment of suspected recurrent gastric cancer after initial surgical resection: is there any effect of FDG-PET/CT in patients' management?
Bilici, Ahmet Erkan; Şeker, Mesut; Öven Ustaalioğlu, Bala Başak; Aslan Canpolat, Nesrin; Tekinsoy, Bülent; Salepçi, Taflan; Gümüş, Mahmut (Oxford University Press, 2010)... -
Clinical value of FDG PET/CT in the diagnosis of suspected recurrent ovarian cancer: is there an impact of FDG PET/CT on patient management?
Bilici, Ahmet Erkan; Öven Ustaalioğlu, Bala Başak; Şeker, Mesut; Aslan Canpolat, Nesrin; Tekinsoy, Bülent; Salepçi, Taflan; Gümüş, Mahmut (Springer, 2010)The aim of this study was to evaluate the clinical value of FDG PET/CT in patients with suspected ovarian cancer recurrence as compared with diagnostic CT, and to assess the impact of the results of FDG PET/CT on treatment ... -
Correlation of caveolin-1 expression with prognosis in patients with gastric cancer after gastrectomy
Şeker, Mesut; Aydın, Dinçer; Bilici, Ahmet; Yavuzer, Dilek; Özgün Geçer, Melin; Özçelik, Melike; Aydın, Özhan; Aliustaoğlu, Mehmet (Karger, 2017)Background: Upregulation of caveolin-1 (Cav-1) expression is correlated with histopathological grade and poor prognosis in several human cancers. However, in gastric cancer, its clinical utility as a useful prognostic ... -
Crizotinib efficacy in alk-positive advanced stage non-small cell lung cancer patients: A real-world experience from Turkey
Kılıçkap, Sadettin; Öztürk, Akın; Karadurmuş, Nuri; Korkmaz, Taner; Yumuk, Perran Fulden; Çiçin, İrfan; Paydaş, Semra; Çılbır, Ebru; Sakalar, Teoman; Uysal, Mükremin; Üskent, Necdet; Demir, Nurcan; Sakin, Ayşegül; Turhal, Nazım Serdar; Keskin, Serhat; Tural, Deniz; Eralp, Yeşim; Buğdaycı Başal, Fatma; Yaşar, Hatime Arzu; Sendur, Mehmet Ali Nahit; Demirci, Umut; Çubukçu, Erdem; Karaağaç, Mustafa; Karaca, Saziye; Tatlı, Ali Murat; Yetişyiğit, Tarkan; Urvay, Semiha; Gürsoy, Pınar; Oyan Uluç, Başak; Turna, Zeynep Hande; Küçüköner, Mehmet; Ölmez, Ömer Fatih; Çabuk, Devrim; Şeker, Mesut; Ünal, Olçun Umut; Meydan, Nezih; Okutur, Sadi Kerem; Tunalı, Duygu (Elsevier Science Inc, 2018)Background: Increasing evidence leads to a ratiocination that genetic heterogeneity of the lung adenocarcinoma patients with sensitive EGFR mutations may impact clinical responses and outcomes to EGFR-TKIs. Method: We ... -
Determine the impact of hybrid capture-based comprehensive genomic profiling (CGP) on the treatment strategies in patients with solid tumors: A national, multicenter, retrospective study
Disel, Umut; Köse, Fatih; Bilici, Ahmet; Özgüroğlu, Mustafa; Sağlam, Sezer; Şeker, Mesut; Aksoy, Sercan; Tek, İbrahim; Eralp, Yeşim; Molinas Mandel, Nil; Demir, Gökhan; Arslan, Çağatay; Demiray, Mutlu; Salepçi, Taflan; Öztürk, Mehmet Akif; Selçukbiricik, Fatih; Temizaş, Gökçe; Fidan, Ebru Gül (American Society of Clinical Oncology, 2020)... -
Efficacy and safety profile of COVID-19 vaccine in cancer patients: A prospective, multicenter cohort study
Yasin, Ayşe İrem; Göktaş Aydın, Sabin; Sümbül, Bilge; Koral, Lokman; Şimsek, Melih; Geredeli, Çağlayan; Öztürk, Akın; Perkin, Perihan; Demirtaş, Derya; Erdemoğlu, Engin; Hacıbekiroğlu, İlhan; Çakır, Emre; Tanrıkulu, Eda; Çoban, Ezgi; Özçelik, Melike; Çelik, Sinemis; Teker, Fatih; Aksoy, Asude; Fırat, Sedat T.; Tekin, Ömer; Kalkan, Ziya; Türken, Orhan; Öven, Bala Başak; Dane, Faysal; Bilici, Ahmet; Işıkdoğan, Abdurrahman; Şeker, Mesut; Türk, Hacı Mehmet; Gümüş, Mahmut (Future Medicine Ltd, 2022)Aim: To compare the seropositivity rate of cancer patients with non-cancer controls after inactive SARS-CoV-2 vaccination (CoronaVac) and evaluate the factors affecting seropositivity. Method: Spike IgG antibodies against ... -
The impact of hybrid capture-based comprehensive genomic profiling on treatment strategies in patients with solid tumors
Dişel, Umut; Köse, Fatih; Bilici, Ahmet; Özgüroğlu, Mustafa; Sağlam, Sezer; Şeker, Mesut; Aksoy, Sercan; Tek, İbrahim; Mandel, Nil Molinas; Demir, Gökhan; Arslan, Çağatay; Demiray, Mutlu; Öztürk, Mehmet Akif; Salepçi, Taflan; Eralp, Yeşim; Selçukbiricik, Fatih; Temizaş, Gökçe; Fidan, Ebru Gül (Turkiye Klinikleri, 2022)Objective: The development of bioinformatics and comprehensive genomic profiling (CGP) has provided insights into the ap-plicability and functionality of the genomic alterations (GA). In this study, we evaluated the impact ... -
Important factors affecting adjuvant treatment decision in stage IA breast cancer patients in Turkey
Öven Ustaalioğlu, Bala Başak; Bilici, Ahmet; Erkol Yılmaz, Burçak; Aliustaoğlu, Mehmet; Şeker, Mesut; Vardar, Fügen; Gümüş, Mahmut (S. Karger AG, 2014)Introduction: In Turkey, the gene expression profile test is not standard, so adjuvant treatment is planned according to clinicopathological factors. Therefore, we retrospectively analyzed important parameters that affect ... -
Platelet to lymphocyte ratio is associated with tumor localization and outcomes in metastatic colorectal cancer
Açıkgöz, Özgür; Çakan, Burçin; Demir, Tarık; Bilici, Ahmet; Öven, Bala Başak; Hamdard, Jamshid; Olmuşçelik, Oktay; Ölmez, Ömer Fatih; Şeker, Mesut; Yıldız, Özcan (Lippincott Williams & Wilkins, 2021)The aim of this study was to investigate the predictive and prognostic value of PLR, and the relationship between PLR and tumor localization. A total of 229 patients with de-novo metastatic CRC were retrospectively analyzed. ... -
Platelet to lymphocyte ratio is associated with tumour localization and outcomes in patients with metastatic colorectal cancer
Bilici, Ahmet; Çakan, Banu; Demir, Tarık; Öven, Bala Başak; Açıkgöz, Özgür; Hamdard, Jamshid; Ölmez, Ömer Fatih; Ölmüşçelik, Olcay; Şeker, Mesut; Yıldız, Özcan (Oxford University Press, 2019)Background The prognostic importance of platelet-to-lymphocyte ratio(PLR)has been also investigated in some cancer types including colorectal cancer (CRC).Several studies have found that PLR is associated with poor prognosis ... -
The prognostic factors for operated gallbladder cancer
Öven Ustaalioğlu, Bala Başak; Bilici, Ahmet; Şeker, Mesut; Kefeli, Umut; Dinçer, Aydın (Oxford University Press, 2017)Introduction: Surgery is the only curative treatment for localized gallbladder cancer. The prognosis is poor because low rate of patients can be found eligible for potential curative surgery. Lymph node metastasis is known ... -
Prognostic factors for regorafenib treatment in patients with refractory metastatic colorectal cancer: A real-life retrospective multi-center study
Göktaş Aydın, Sabin; Kavak, Engin Eren; Topçu, Atakan; Bayramgil, Ayberk; Akgül, Fahri; Kahraman, Seda; Aykan, Musa Barış; Altıntaş, Yunus Emre; Helvacı, Kaan; Ürün, Yüksel; Bilici, Ahmet; Şeker, Mesut (Association of Basic Medical Sciences of FBIH, 2023)Regorafenib, an oral multikinase inhibitor, has improved survival in metastatic colorectal cancer (mCRC) patients who have progressed on standard therapies. Our study aimed to evaluate prognostic factors influencing ... -
Prognostic significance of HER2 loss after HER2-targeted neoadjuvant treatment in patients with HER2-positive locally advanced breast cancer
Kutlu, Yasin; Çekin, Ruhper; Göktaş Aydın, Sabin; Shbair, Abdallah T. M.; Bilici, Ahmet; Arıcı, Serdar; Öven, Bala Başak; Açıkgöz, Özgür; Özcan, Erkan; Ölmez, Ömer Fatih; Çakır, Aslı; Şeker, Mesut (2024)Loss of human epidermal growth factor receptor 2 (HER2) expression can be seen in almost 25–30 % patients after HER2 receptor directed neoadjuvant treatment. These patients have unclear clinical outcomes in previous studies. ... -
Prognostic significance of metastatic lymph node ratio in patients with pN3 gastric cancer who underwent curative gastrectom
Bilici, Ahmet; Biricik, Fatih Selçuk; Şeker, Mesut; Öven, Başak Bala; Ölmez, Ömer Fatih; Yıldız, Özcan; Ölmüşçelik, Oktay; Hamdard, Jamshid; Açıkgöz, Özgür; Çakır, Aslı; Kapran, Yersu; Balık, Emre; Öncel, Mustafa (Karger, 2019)Background: Lymph node involvement is an important prognostic factor in patients with gastric cancer. The aim of this study was to determine the prognostic significance of metastatic lymph node ratio (MLNR) and compare it ... -
Prognostic significance of positive lymph node ratio in patients with pN3 gastric cancer who underwent curative gastrectomy
Bilici, Ahmet; Şeker, Mesut; Öven Ustaalıoğlu Bala, Başak; Ölmez, Ömer Fatih; Yıldız, Özcan; Çakır, Aslı; Çağlar, Hale Başak; Öncel, Mustafa (Oxford University Press, 2017)Introduction: Lymph node metastasis is an important prognostic factor for patients with gastric cancer. The aim of this study was to determine the prognostic significance of metastatic lymph node ratio (MLNR) in pN3 gastric ... -
Prognostic significance of primary tumor localization in patients with metastatic colorectal cancer: Is it beneficial to select targeted treatment? Real-life experience from Turkey
Çakan, Burçin; Açıkgöz, Özgür; Bilici, Ahmet; Demir, Tarık; Öven, Bala Başak; Hamdard, Jamshid; Olmuşçelik, Oktay; Ölmez, Ömer Fatih; Şeker, Mesut; Yıldız, Özcan (Zerbinis Publications, 2021)Purpose: The purpose of this study was to investigate the prognostic value,and the effect of primary tumor location on targeted therapy selection in patients with metastatic colorectal cancer (mCRC). Methods: A total of ...