Yazar "Cansız, Derya" için listeleme
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Quantitative real-time PCR method to evaluate gene expression in zebrafish embryos
Beler, Merih; Cansız, Derya; Ünal, İsmail; Emekli Alturfan, Ebru (Humana Press Inc., 2024)The fast zebrafish embryonic development offers an opportunity for the study of genes crucial for developmental processes. Several genes associated with human diseases have orthologs in zebrafish. Enhanced comprehension ... -
Sodium-dependent glucose co-transporter-2 inhibitor empagliflozin exerts neuroprotective effects in rotenone-induced Parkinson's disease model in zebrafish; mechanism involving ketogenesis and autophagy
Ünal, İsmail; Cansız, Derya; Beler, Merih; Sezer, Zehra; Güzel, Elif; Emekli Alturfan, Ebru (Elsevier B.V., 2023)Sodium-dependent glucose co-transporter-2 (SGLT2) inhibitor empagliflozin (EMP), is the new class of oral hypoglycemic agent approved as a treatment for Type 2 diabetes. SGLT2 inhibitors may induce ketogenesis through ... -
Stevioside ameliorates hyperglycemia and glucose intolerance, in a diet-induced obese zebrafish model, through epigenetic, oxidative stress and inflammatory regulation
Dandin, Esra; Üstündağ, Ünsal Veli; Ünal, İsmail; Ateş Kalkan, Perihan Seda; Cansız, Derya; Beler, Merih; Ak, Esin; Alturfan, A. Ata; Emekli Alturfan, Ebru (Elsevier Ltd, 2022)Obesity is an independent risk factor for type 2 diabetes and epigenetic regulatory mechanisms affect obesityrelated mechanisms. Due to weight gain concern in society, artificial sweeteners with no nutritional value have ... -
Stevioside improves brain oxidant-antioxidant status in overfed zebrafish
Dandin, Esra; Ünal, İsmail; Beler, Merih; Üstündağ, Ünsal Veli; Cansız, Derya; Ateş Kalkan, Perihan Seda; Emekli Alturfan, Ebru (Istanbul University Press, 2023)Objective: An excessive buildup of adipose tissue is a defining feature of overnutrition, and a significant fraction of the world's population suffers from obesity. Overnutrition is associated with the deterioration of ... -
Whole-mount RNA in situ hybridization of zebrafish embryos
Ünal, İsmail; Cansız, Derya; Beler, Merih; Alturfan, Ahmet Ata; Emekli Alturfan, Ebru (Humana Press Inc., 2024)A commonly employed technique in molecular biology to evaluate the temporal and spatial expression of a certain gene is in situ hybridization. This method is an effective strategy to construct synexpression groups, ...