Ara
Toplam kayıt 192, listelenen: 11-20
Isolation of anti-inflammatory compounds from Sambucus ebulus leaves through in vitro activity-guided fractionation
(Georg Thieme Verlag, 2015)
The in vitro anti-inflammatory effects of subextracts (n-hexane, chloroform, ethyl acetate, n-butanol, remaining water) of the methanol extract of the leaves of Sambucus ebulus L. (Adoxaceae) were investigated for their ...
Biological activities and chemical constituents of ferula anatolica boiss
(Georg Thieme Verlag Kg, 2013)
Genus Ferula has about 185 species and widely distributed through out Central Asia, China, Afghanistan, India, Syria, Palestine, Israel, North Africa, North America, South-West and Central Europe. Currently, 23 species and ...
The determine of possible drug interaction of clarithromycin
(Springer, 2016)
Phenytoin is an antiepileptic drug which is eliminated by CYP2C9, CYP2C19 (less important: CYP2C18, CYP3A4) enzyme. Therapeutic concentration range is very important due to the narrow therapeutic drug levels. Targeted ...
Prescribing pattern of PPI and clopidogrel in community pharmacies in Turkey
(Springer, 2016)
Background & Objectives: Proton Pump Inhibitors (PPIs) are among the most prescribed medications in Turkey. The use of proton pump inhibitors is one of the risk factors associated with treatment failure or unresponsiveness ...
Design and synthesis of stable N-[2-(Aryl/heteroaryl substituted)ethyl] propanamide derivatives of (S)-ketoprofen and (S)-ibuprofen as non-ulcerogenic anti-inflammatory and analgesic agents
(University of Istanbul, 2016)
The carboxylic acid groups of (S) ketoprofen and (S) ibuprofen were brought into reaction with substituted ethylamine derivatives to form (S)-2-(4-isobutylphenyl)- and (S)-2-(3-benzoylphenyl)-N-[2-(aryl/heteroaryl substituted) ...
Synthesis, structure elucidation and determination of acid dissociation constant, tautomerism of pyrido [1,2-a] benzimidazole-2,4-dione
(University of Istanbul, 2016)
The first starting material, 1H-2-acetylbenzimidazole, 4, was synthesized by o-phenylenediamine, 1, and lactic acid solution, 2, in hydrochloric acid medium on the first step than, oxidation reaction was performed by CrO3 ...
Synthesis of novel 3, 5, 6-trisubstituted triazine derivatives and their biological activity evaluation as potential antitumor and anti-inflammatory agents
(University of Istanbul, 2016)
In this study, new 3, 5, 6-trisubstituted 1, 2, 4-triazine derivatives (1-9) were synthesized and their structures were determined by using NMR, IR and Mass spectroscopic methods. In vitro antitumor activities against MCF-7 ...
DNA damage in gasoline station workers caused by occupational exposure to petrol vapour in Turkey
(University of Istanbul, 2016)
The refueling of vehicles is a major source of volatile organic compounds generated by used and evaporated fuel. Gasoline workers are directly exposed to various fuel products via many routes in the ambient air. The aim ...
Synthesis and antimicrobial activity evaluation of novel nitrofuranthiazoles
(University of Istanbul, 2016)
In this work, six novel 4-aryl-2-[2-((5-nitrofuran-2-yl)methylene)hydrazinyl] thiazole derivatives (2a-f) were synthesized starting from 5-nitro-2-furaldehyde diacetate by using Hantzsch thiazole synthesis. The antimicrobial ...
In vitro anti-helicobacter pylori and antimycobacterial activity evaluation of selected plants from Turkey
(2020)
In this study, the extracts of Ulmus minor Mill. subsp. minor (Ulmaceae), Lathyrus pratensis L. (Leguminosae), Glaucium leiocarpum Bois. (Papaveraceae), and Echium vulgare L. (Boraginacea) were investigated for their in ...