| dc.contributor.author | Yurttaş, Leyla | |
| dc.contributor.author | Duran, Murat | |
| dc.contributor.author | Demirayak, Şeref | |
| dc.contributor.author | Gençer Karaca, Hülya | |
| dc.contributor.author | Tunalı, Yağmur | |
| dc.date.accessioned | 10.07.201910:49:13 | |
| dc.date.accessioned | 2019-07-10T19:37:27Z | |
| dc.date.available | 10.07.201910:49:14 | |
| dc.date.available | 2019-07-10T19:37:27Z | |
| dc.date.issued | 2013 | en_US |
| dc.identifier.citation | Yurttaş, L., Duran, M., Demirayak, Ş., Gençer Karaca, H. ve Tunalı, Y. (2013). Synthesis and initial biological evaluation of substituted 1-phenylamino-2-thio-4,5-dimethyl-1H-imidazole derivatives. Bioorganic and Medicinal Chemistry Letters, 23(24), 6764-6768. https://dx.doi.org/10.1016/j.bmcl.2013.10.024 | en_US |
| dc.identifier.issn | 0960-894X | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12511/1406 | |
| dc.identifier.uri | https://dx.doi.org/10.1016/j.bmcl.2013.10.024 | |
| dc.description.abstract | In this work, some new 2-[(4,5-dimethyl-1-(arylamino)-1H-imidazol-2-yl) thio]-1-(aryl)ethanone derivatives were synthesized and investigated for their antibacterial, antifungal and anticancer activities. Toxicity of the most effective compounds was established by performing Brine-Shrimp lethality assay. Antifungal activity of the compounds was found to be higher than antibacterial and anticancer activities of the compounds. | en_US |
| dc.language.iso | eng | en_US |
| dc.rights | info:eu-repo/semantics/embargoedAccess | en_US |
| dc.subject | Anticancer | en_US |
| dc.subject | Antimicrobial | en_US |
| dc.subject | Brine-Shrimp Test | en_US |
| dc.subject | Imidazole | en_US |
| dc.title | Synthesis and initial biological evaluation of substituted 1-phenylamino-2-thio-4,5-dimethyl-1H-imidazole derivatives | en_US |
| dc.type | article | en_US |
| dc.relation.ispartof | Bioorganic and Medicinal Chemistry Letters | en_US |
| dc.department | İstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmasötik Kimya Ana Bilim Dalı | en_US |
| dc.identifier.volume | 23 | en_US |
| dc.identifier.issue | 24 | en_US |
| dc.identifier.startpage | 6764 | en_US |
| dc.identifier.endpage | 6768 | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.identifier.doi | 10.1016/j.bmcl.2013.10.024 | en_US |
| dc.identifier.wosquality | Q2 | en_US |
| dc.identifier.scopusquality | Q1 | en_US |
