The diagnostic role of "acceleration time" measurement in patients with classical low flow low gradient aortic stenosis with reduced left ventricular ejection fraction
Erişim
info:eu-repo/semantics/closedAccessTarih
2023Yazar
Memiç Sancar, KadriyeBabur Güler, Gamze
Tanboğa, Halil İbrahim
Türkvatan Cansever, Aysel
Demir, Ali Rıza
Güler, Arda
Tekin, Meltem
Uygur, Begüm
Birant, Ali
Avcı, Yalçın
Güler, Ekrem
Ertürk, Mehmet
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Memiç Sancar, K., Babur Güler, G., Tanboğa, H. İ., Türkvatan Cansever, A., Demir, A. R., Güler, A. ... Ertürk, M. (2023). The diagnostic role of "acceleration time" measurement in patients with classical low flow low gradient aortic stenosis with reduced left ventricular ejection fraction. International Journal of Cardiovascular Imaging, 39(3), 481-489. https://dx.doi.org/10.1007/s10554-022-02745-2Özet
Purpose In our study, we aimed to assess the role of acceleration time (AT), ejection time (ET), and AT/ET ratio to distinguish between true and pseudo severe AS in patients with classical low flow-low gradient (LF-LG) aortic stenosis (AS) with reduced left ventricular ejection fraction (LVEF).
Methods Sixty-seven classical LF-LG AS with reduced LVEF patients who underwent dobutamine stress echocardiography (DSE) were included in the study. According to DSE results, all patients were divided into two groups; true AS and pseudo severe AS. Aortic valve calcium score was measured in patients with inconclusive DSE results. AT and other ejection dynamics (ET and AT/ET) were calculated by taking baseline echocardiographic records into account for all patients. The predictive power of AT and other ejection dynamics were evaluated to estimate true and pseudo severe AS.
Results According to DSE results, out of 67 patients, 44 (65.7%) was diagnosed as true severe AS. There was a statistically significant relation between baseline AT and true AS [adjusted OR 4.47 (95% CI 1.93-10.4), p = 0.001]. The best cutoff value of AT was measured as 100 msec according to the Youden index. This value had a sensitivity value of 77%, specificity value of 87%, positive predictive value of 92%, and a negative predictive value of 67%.
Conclusion The measurement of AT can predict the DSE outcome and can be used for diagnostic purposes to distinguish between true and pseudo severe AS in classical LF-LG AS patients with reduced LVEF.
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International Journal of Cardiovascular ImagingCilt
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