Matrix metalloproteinase-9, neuron-specific enolase, S100 B and tau protein levels in the patients with carbon monoxide poisoning
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Erişim
info:eu-repo/semantics/openAccessTarih
2023Yazar
Can, BasriZengin, Suat
Eren, Şevki Hakan
Boğan, Mustafa
Sabak, Mustafa
Gülen, Bedia
Ulusal, Hasan
Sunar, Mehmet Mustafa
Karaduman, Muhammet Esat
Taysi, Seyithan
Üst veri
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Can, B., Zengin, S., Eren, Ş. H., Boğan, M., Sabak, M., Gülen, B. ... Taysi, S. (2023). Matrix metalloproteinase-9, neuron-specific enolase, S100 B and tau protein levels in the patients with carbon monoxide poisoning. New Emirates Medical Journal, 4(2). https://dx.doi.org/10.2174/0250688204666230508115135Özet
Background: S100B, NSE, MMP-9, and Tau protein levels increase in cases causing hypoxic cell damage. The diagnosis of the severity of carbon monoxide (CO) poisoning in the early period of these parameters was studied. Material and Methods: COHb level measurement was made using a signal capture CO-pulse oximeter (Masimo's SET Rainbow, Masimo's Co, USA) at the first admission of the patients. Then, COHb levels were confirmed by arterial blood gas(ABG) analysis. The patients were divided into two groups as mild and moderate-severe, according to their Glasgow coma scores (GCS) [Mild (14–15); Moderate (9–13) or Severe (3–8)]. The control group was composed of 16 healthy and non-smoking volunteers. Results: The serum S100B protein and MMP-9 values at 0 hr of admission in the hospital and 3hr of treatment were not significantly different in the patient group as compared to the control group. Tau protein levels were significantly higher in the patient group at 0 and 3 hours (p> 0.05) as compared to healthy person. Conclusion: There was no relationship between CO poisoning and MMP-9 and S100B protein levels. NSE and Tau protein were significantly higher in the patient group than the control group. Tau protein may be more useful marker as compared to neuron-specific enolase.
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Q4Kaynak
New Emirates Medical JournalCilt
4Sayı
2Bağlantı
https://dx.doi.org/10.2174/0250688204666230508115135https://hdl.handle.net/20.500.12511/11372
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